YY1 Protein (His tag)

Catalog No. ABIN7319105

Product Details

Target: YY1 (YY1 Transcription Factor (YY1))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This YY1 protein is labelled with His tag.

Purpose: Recombinant Human YY1 Protein (His Tag)

Sequence: Val221-Gly321

Characteristics: Recombinant Human Yin and Yang 1 protein/Transcriptional repressor protein YY1 is produced by our E.coli expression system and the target gene encoding Val221-Gly321 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: YY1 (YY1 Transcription Factor (YY1))

Alternative Name: YY1 (YY1 Products)

Synonyms: yy1-a Protein, FIII Protein, MGC83714 Protein, yy1l Protein, zgc:64207 Protein, YY1 Protein, LOC494431 Protein, xyy1 Protein, delta Protein, nf-e1 Protein, ucrbp Protein, yin-yang-1 Protein, LOC100304682 Protein, ino80s Protein, yy1 Protein, DELTA Protein, INO80S Protein, NF-E1 Protein, UCRBP Protein, YIN-YANG-1 Protein, AW488674 Protein, fb59g10 Protein, wu:fa16g07 Protein, wu:fb59g10 Protein, YY1 transcription factor L homeolog Protein, YY1 transcription factor b Protein, YY1 transcription factor Protein, transcriptional repressor protein YY1 Protein, YY1 transcription factor S homeolog Protein, YY1 transcription factor a Protein, YY2 transcription factor Protein, yy1.L Protein, yy1b Protein, YY1 Protein, yy1 Protein, LOC100304682 Protein, yy1.S Protein, Yy1 Protein, yy1a Protein, YY2 Protein

Background:

Background: Transcriptional repressor protein YY1(YY1)contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. The effect on transcription regulation of the protein is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect activation or repression via cofactor recruitment, or activation or repression by disruption of binding sites or conformational DNA changes. Its activity is regulated by transcription factors and cytoplasmic proteins that have been shown to abrogate or completely inhibit YY1-mediated activation or repression.

Synonym: Transcriptional repressor protein YY1,Delta transcription factor,INO80 complex subunit S,NF-E1,Yin and yang 1,INO80S

Molecular Weight: 12.6 kDa

UniProt: P25490