anti-Zinc Finger, AN1-Type Domain 2B (ZFAND2B) Antibodies

ZFAND2B encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. Additionally we are shipping Zinc Finger, AN1-Type Domain 2B Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZFAND2B 68818 Q91X58
ZFAND2B 363253 Q4KLG9
ZFAND2B 130617 Q8WV99
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Top anti-Zinc Finger, AN1-Type Domain 2B Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB Host: Rabbit Target Name: ZFAND2B Sample Type: HepG2 Whole Cell lysates Antibody Dilution: 1.0ug/ml 100 μL 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL 11 to 14 Days
$522.50
Details
Human Mouse Un-conjugated IF, WB 100 μL 11 to 14 Days
$522.50
Details
Human Rabbit Un-conjugated WB 100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 200 μL 12 to 14 Days
$438.90
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with ZFAND2B polyclonal antibody  at 1:250-1:500 dilution. Immunohistochemical staining of human kidney with ZFAND2B polyclonal antibody  shows strong cytoplasmic and nuclear positivity in cells in tubules at 1:10-1:20 dilution. 100 μL 11 to 12 Days
$577.33
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg 11 to 16 Days
$405.08
Details
Human Rabbit Biotin   100 μL 2 to 3 Days
$394.90
Details
Human Rabbit Alexa Fluor 488   100 μL 2 to 3 Days
$416.90
Details

Top referenced anti-Zinc Finger, AN1-Type Domain 2B Antibodies

  1. Human Polyclonal ZFAND2B Primary Antibody for ICC, IF - ABIN4366812 : Osorio, Soria-Valles, Santiago-Fernández, Bernal, Mittelbrunn, Colado, Rodríguez, Bonzon-Kulichenko, Vázquez, Porta-de-la-Riva, Cerón, Fueyo, Li, Green, Freije, López-Otín: Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling. in Nature medicine 2016 (PubMed)

More Antibodies against Zinc Finger, AN1-Type Domain 2B Interaction Partners

Mouse (Murine) Zinc Finger, AN1-Type Domain 2B (ZFAND2B) interaction partners

  1. Study demonstrates specificity of AIRAPL for Lys48-linked tri-ubiquitin chains triggered by intrinsic selectivity of its double-sided UIM (UIM2) for Lys48 linkage and a flexible inter-UIM linker that results in an overall conformation which confers simultaneous binding of tUIMs to three consecutive ubiquitin moieties in a Lys48-linked chain.

  2. AIRAPL-deficient mice develop a fully-penetrant myeloproliferative neoplastic process via dysregulation of IGF1/IGF1R.

Human Zinc Finger, AN1-Type Domain 2B (ZFAND2B) interaction partners

  1. Results demonstrate that on specific translocation inhibition, a p97-AIRAPL complex directly binds and regulates the efficient processing of polyubiquitinated pQC substrates by the UPS. Results also demonstrate p97's role in pQC processing of preproinsulin in cases of naturally occurring mutations within the signal sequence of insulin.

  2. Consistent with its proposed role as a tumor suppressor of myeloid transformation, AIRAPL expression is widely abrogated in human myeloproliferative disorders.

  3. Zinc finger proteins may be associated with pathophysiology of severe dry eye syndrome.

  4. AIRAPL binds to p97 and forms a complex in the endoplasmic reticulum membrane.

  5. An AIP-1 human homologue, ZFAND2B, has a similar protective effect against Abeta toxicity.

Zinc Finger, AN1-Type Domain 2B (ZFAND2B) Antigen Profile

Protein Summary

This gene encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. The encoded protein likely associates with the proteosome to stimulate the degradation of toxic or misfolded proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with ZFAND2B

  • zinc finger, AN1 type domain 2B (Zfand2b) antibody
  • zinc finger AN1-type containing 2B (Zfand2b) antibody
  • zinc finger AN1-type containing 2B (ZFAND2B) antibody
  • 1110060O18Rik antibody
  • AIRAPL antibody
  • C81256 antibody
  • RGD1306260 antibody

Protein level used designations for ZFAND2B

AIRAP-like protein , AN1-type zinc finger protein 2B , arsenite-inducible RNA-associated protein-like protein

GENE ID SPECIES
68818 Mus musculus
363253 Rattus norvegicus
130617 Homo sapiens
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