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ZMIZ1 encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins.
Showing 10 out of 53 products:
Human Polyclonal ZMIZ1 Primary Antibody for IHC (p), WB - ABIN390174
Rakowski, Garagiola, Li, Decker, Caruso, Jones, Kuick, Cierpicki, Maillard, Chiang: Convergence of the ZMIZ1 and NOTCH1 pathways at C-MYC in acute T lymphoblastic leukemias. in Cancer research 2013
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we have identified a molecular phenotype of MS defined by expression of the MS risk gene ZMIZ1 in blood, and by other genes, especially transcription factors. ZMIZ1 expression is affected by, and interacts with, the environmental risk factors EBV and Vitamin D.
rs1250569 (ZMIZ1) and rs10114470 (TL1A) are two novel loci that indicate susceptibility to Inflammatory Bowel Disease in Han-Chinese patients.
This case represents the first constitutional balanced translocation disrupting and fusing both MIZ-type containing and proline-rich 12 and provides clues for the potential function and effects of these in the central nervous system.
At the ZMIZ1 locus, we show that perturbation of ZMIZ1 expression in human islets and beta-cells influences exocytosis and insulin (show INS Antibodies) secretion, highlighting a novel role for ZMIZ1 in the maintenance of glucose homeostasis.
Targeting the NOTCH1 (show NOTCH1 Antibodies)-ZMIZ1 interaction might combat leukemic growth.
the expression of SENP8 (show SENP8 Antibodies), SAE1 (show SAE1 Antibodies), PIAS1 (show PIAS1 Antibodies), PIAS2 (show PIAS2 Antibodies) and ZMIZ1 is deregulated in the majority of PTC (show F9 Antibodies) tissues, likely contributing to the PTC (show F9 Antibodies) phenotype.
ZMIZ1 is a susceptibility gene for vitiligo (show MITF Antibodies) in Chinese population.
ZMIZ1 is overexpressed in a significant percentage of human breast, ovarian, and colon cancers in addition to human squamous cell carcinomas, suggesting that ZMIZ1 may play a broader role in epithelial cancers.
ZMIZ1 and activated NOTCH1 ar (show NOTCH1 Antibodies)e coexpressed in a subset of human T-ALL patients and cell lines.
First line of evidence demonstrates a physiological (show SMAD3 Antibodies) role for endogenous Zimp10 in regulating Smad3/4-mediated transcription.
Ectopic expression of Zmiz1 induces cutaneous squamous cell malignancies in a mouse model of cancer.
we show that activated NOTCH1 (show NOTCH1 Antibodies) and ZMIZ1 collaborate to induce T-ALL in mice.
Zimp10 is found in somatic cells, outside the testis cords and ceases to be expressed in the adult testis.
A physiological role for Zimp10 in regulating Smad3 (show SMAD3 Antibodies)/4-mediated transcription is demonstrated in mouse embryonic fibroblasts.
provides evidence to demonstrate a crucial role for Zimp10 in vasculogenesis
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia.
zinc finger, MIZ-type containing 1
, zinc finger MIZ domain-containing protein 1-like
, retinoic acid induced 17-like
, FLJ00092 protein
, retinoic acid induced 17
, zinc finger MIZ domain-containing protein 1
, zinc finger-containing, Miz1, PIAS-like protein on chromosome 10
, PIAS-like protein Zimp10
, retinoic acid-induced protein 17
, PIAS-like protein hZimp10