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ZNF124 encodes a member of the Kruppel-type (C2H2) zinc finger protein family. Additionally we are shipping Zinc Finger Protein 124 Antibodies (44) and and many more products for this protein.
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RNA-Seq evidence for lung tissue-specific monoallelic expression of ZNF124, located 363 kb upstream of the GCSAML somatic (secondary), imprinted differentially methylated region (iDMR). The ZNF124 locus has no overlapping hemimethylated CGIs in normal tissues, including lung tissue The GCSAML iDMR might regulate the lung tissue-specific, monoallelic expression of ZNF124. In the placenta, ZNF124 is biallelically expressed.
This gene encodes a member of the Kruppel-type (C2H2) zinc finger protein family. It has a KRAB-A box at its amino terminus and seven consecutively repeated zinc finger motifs at its carboxy terminus. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and its expression inhibits apoptotic cell death induced by irradiation or exposure to etoposide. These attributes suggest that this protein may act as a transcription factor. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described for this gene but their biological validity has not been confirmed. This gene has a pseudogene on chromosome 14.
zinc finger protein 124
, zinc finger protein 124 (HZF-16)
, zinc finger protein HZF-16