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Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Additionally we are shipping ZSCAN10 Proteins (1) and many more products for this protein.
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The pluripotency factor ZSCAN10 is poorly expressed in A-iPSCs and addition of ZSCAN10 to the four Yamanaka factors (OCT4 (show POU5F1 Antibodies), SOX2 (show SOX2 Antibodies), KLF4 (show KLF4 Antibodies) and c-MYC (show MYC Antibodies)) during A-iPSC reprogramming normalizes ROS (show ROS1 Antibodies)-glutathione homeostasis and the DNA damage response, and recovers genomic stability.
We demonstrated that SLC16A5 (show SLC16A5 Antibodies) and ZNF206 displayed altered methylation patterns in the neuroblastoma (show ARHGEF16 Antibodies) genome
Data indicates that changes in DNA methylation (show HELLS Antibodies) levels at the Zfp206-exon 5 might be one of the important factors during neuronal development in mice and the hypomethylation of the homologous region induced ZNF206 expression in humans.
Our results clearly indicate that Zscan10 is dispensable for the ability of self-renewal and differentiation in ES cells.
a role for Zscan10 in either maintaining progenitor cell subpopulation or impacting on fate choice decisions thereof
Zfp206 is a regulator of embryonic stem cell differentiation that controls a set of genes expressed very early in development, most of which themselves appear to be regulators.
Zfp206 is an embryonic transcription factor that plays a role in regulating pluripotency of embryonic stem cells.
Zfp206 is a key component of the transcriptional regulatory network and together with Oct4 (show POU5F1 Antibodies) and Sox2 (show SOX2 Antibodies) regulates differentiation of embryonic stem cells.
Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'--3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4.
zinc finger and SCAN domain-containing protein 10
, zinc finger protein 206
, zinc finger and SCAN domains 10
, zinc finger with KRAB and SCAN domains 10