Zinc and Ring Finger Protein 1 Proteins (ZNRF1)

ZNRF1 encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Additionally we are shipping ZNRF1 Antibodies (68) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ZNRF1 84937 Q8ND25
Mouse ZNRF1 ZNRF1 170737 Q91V17
Rat ZNRF1 ZNRF1 690769  
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Top ZNRF1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 50 Days
$6,749.58
Details
Wheat germ Human GST tag 10 μg 11 to 12 Days
$414.29
Details
Yeast Xenopus tropicalis His tag   1 mg 60 to 71 Days
$2,467.67
Details
Yeast Cow His tag   1 mg 60 to 71 Days
$2,566.67
Details
Escherichia coli (E. coli) Human His tag   10 μg 15 to 16 Days
$300.00
Details

ZNRF1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for Zinc and Ring Finger Protein 1 (ZNRF1) Interaction Partners

Human Zinc and Ring Finger Protein 1 (ZNRF1) interaction partners

  1. as a consequence of its high E2 affinity, an excess of ZNRF1 inhibits Ube2N-mediated ubiquitination at concentrations >/=500 nM instead of showing enhanced ubiquitination

  2. rs17684886 (ZNRF1) and rs599019 (COLEC12) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1) and rs899036 (API5) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes

  3. ZNRF1 and ZNRF2 are new players in regulation of the ubiquitous Na(+)/K(+)ATPase that is tuned to changing demands in many physiological contexts.

  4. data suggest that ZNRF proteins play a role in the establishment and maintenance of neuronal transmission and plasticity via their ubiquitin ligase activity

  5. These results suggest that ZNRF1 mediates regulation of neuritogenesis via interaction with tubulin.

Mouse (Murine) Zinc and Ring Finger Protein 1 (ZNRF1) interaction partners

  1. This study defines ZNRF1 as a regulator of TLR4-induced inflammatory responses and reveals another mechanism for the regulation of TLR4 signalling through CAV1.

  2. up-regulation of ZNRF1 activity by oxidative stress leads to neuronal apoptosis and Wallerian degeneration.

  3. The ZNRF1-AKT-GSK3B-CRMP2 pathway plays an important role in controlling Wallerian degeneration.

ZNRF1 Protein Profile

Protein Summary

This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons.

Gene names and symbols associated with ZNRF1

  • zinc and ring finger 1 (ZNRF1)
  • zinc and ring finger 1 (Znrf1)
  • zinc and ring finger 1 (znrf1)
  • zinc and ring finger 1, E3 ubiquitin protein ligase S homeolog (znrf1.S)
  • B830022L21Rik protein
  • nin283 protein
  • Rnf42 protein
  • zgc:77896 protein
  • zrfp1 protein

Protein level used designations for ZNRF1

E3 ubiquitin-protein ligase ZNRF1 , nerve injury gene 283 , nerve injury-induced gene 283 protein , zinc and ring finger protein 1 , zinc/RING finger protein 1 , peripheral nerve injury protein nin283 , ring finger protein 42 , zinc ring finger protein 1 , E3 ubiquitin-protein ligase znrf1

GENE ID SPECIES
84937 Homo sapiens
170737 Mus musculus
509076 Bos taurus
690769 Rattus norvegicus
393844 Danio rerio
380496 Xenopus laevis
425231 Gallus gallus
100730744 Cavia porcellus
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