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Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes.
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Dog (Canine) Polyclonal Fetuin A Primary Antibody for WB - ABIN2778140
Ix, Shlipak, Brandenburg, Ali, Ketteler, Whooley: Association between human fetuin-A and the metabolic syndrome: data from the Heart and Soul Study. in Circulation 2006
Show all 3 Pubmed References
Human Polyclonal Fetuin A Primary Antibody for IHC, IHC (p) - ABIN4311401
Hossain, De Souza, Bagul, MacPhee, Kessaris, Morsy: HSP70, Peroxiredoxin-3 and -6 are upregulated during renal warm ischaemia in a donation after circulatory death model. in Journal of proteomics 2014
Show all 2 Pubmed References
Human Polyclonal Fetuin A Primary Antibody for IF (p), IHC (p) - ABIN681733
Naito, Hashimoto, Watanabe, Shirai, Takahashi, Kojima, Watanabe, Sato, Iso, Matsuyama, Suzuki, Ishibashi-Ueda, Watanabe: Facilitatory effects of fetuin-A on atherosclerosis. in Atherosclerosis 2016
Cow (Bovine) Polyclonal Fetuin A Primary Antibody for ELISA, SimWes - ABIN253553
Blome, Petro, Schengrund: Surface plasmon resonance analysis of ricin binding to plasma membranes isolated from NIH 3T3 cells. in Analytical biochemistry 2009
Human Monoclonal Fetuin A Primary Antibody for ELISA, WB - ABIN559818
Quaresima, Crugliano, Gaspari, Faniello, Cosimo, Valanzano, Genuardi, Cannataro, Veltri, Baudi, Doldo, Cuda, Venuta, Costanzo: A proteomics approach to identify changes in protein profiles in serum of Familial Adenomatous Polyposis patients. in Cancer letters 2009
Human Polyclonal Fetuin A Primary Antibody for IHC, IHC (p) - ABIN4311402
Lorenzen, Martino, Scheffner, Bröcker, Leitolf, Haller, Gwinner: Fetuin, matrix-Gla protein and osteopontin in calcification of renal allografts. in PLoS ONE 2013
Cow (Bovine) Polyclonal Fetuin A Primary Antibody for ELISA - ABIN2477504
Raglin, Morgan, Luchsinger: Mood and self-motivation in successful and unsuccessful female rowers. in Medicine and science in sports and exercise 1991
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Human Monoclonal Fetuin A Primary Antibody for ELISA, ELISA (Detection) - ABIN1996377
Zheng, Li, Zhang, Zhou, Ma, Zhou, Chen, Lin: Salivary biomarkers indicate obstructive sleep apnea patients with cardiovascular diseases. in Scientific reports 2014
Although there is mechanistic evidence for an effect of fetuin-A on insulin (show INS Antibodies) sensitivity and secretion, data from this study does not support a strong, relevant relationship between circulating fetuin-A and risk of diabetes type 2 in the general European population studied.
In overweight-to-obese older men, exercise/weight loss therapy appears to increase plasma fetuin-A levels, which is related to improvements in aerobic capacity.
Higher fetuin-A levels are associated with incident type 2 diabetes in both males and females.
Data suggest that plasma fetuin-A levels are down-regulated in type 2 diabetes with peripheral arterial disease, irrespective of traditional cardiovascular risk factors; fetuin-A may be involved in lower extremity arterial calcification in type 2 diabetes.
Data suggest that, in children with type I diabetes, serum levels of osteoprotegerin (show TNFRSF11B Antibodies) are up-regulated, serum levels of RANKL (show TNFSF11 Antibodies) are unchanged, and serum levels of fetuin-A are down-regulated. (RANKL (show TNFSF11 Antibodies) = receptor activator of nuclear factor kappa B ligand (show TNFSF11 Antibodies))
Elevated levels of pentraxin-3 (show PTX3 Antibodies), fetuin-A, CRP (show CRP Antibodies), ESR (show ESR1 Antibodies) might play a role in the pathogenesis of rheumatoid arthritis. Levels of fetuin-A, insulin (show INS Antibodies) HOMA-IR, pentraxin-3 (show PTX3 Antibodies), CRP (show CRP Antibodies) and ESR (show ESR1 Antibodies) were not associated with clinical severity of the rheumatoid arthritis.
the studies demonstrate the impact of fetuin-A as significant node of growth, motility, and invasion signaling in glioblastomas that can be targeted for therapy.
Lower plasma fetuin-A levels were associated with an increased risk of all-cause and CVD mortality in patients with coronary artery disease independently of traditional CVD risk factors.
The over-secretion of alpha-2-Heremans-Schmid glycoprotein by visceral adipose tissue, the increased secretion of the active phosphorylated form by subcutaneous adipose tissuein obese animals, and the adipose-derived alpha-2-Heremans-Schmid glycoprotein capacity to inhibit the insulin (show INS Antibodies) pathway suggest the participation of adipose-derived alpha-2-Heremans-Schmid glycoprotein in the deleterious effects of obesity.
AHSG can be used to distinguish between inflammatory bowel disease and irritable bowel syndrome patients or healthy controls while at the same time "predicting" complicated disease behavior, need for therapy escalation and surgery.
two glycoproteins, AHSG and HPX (show HPX Antibodies), represent a pivotal glycoprotein of the cytoprotective activity for WN1316, showing a concrete evidence for the novel glycan-independent function of serum glycoproteins in neuroprotective drug efficacy.
Site-specific analysis of the O-glycosylation of bovine fetuin by electron-transfer dissociation mass spectrometry.
These experiments revealed a second mechanism of long-term mineral ion stabilization by the fetuin-A that is complementary to the formation of calciprotein particles.
The growth plate slippage occurred in 70% of Ahsg-/- mice of both sexes around three weeks postnatal.
AHSG is produced in bone, mainly in osteocytes and also show for the first time that its production is modulated by FGF23 (show FGF23 Antibodies).
These findings establish urinary Fetuin-A as a sensitive biomarker of the progression of autosomal dominant polycystic kidney disease.
Plasma levels of the calcification inhibitor fetuin-A were significantly decreased in CKD animals compared to controls.
fetuin-A regulates endochondral ossification through mineralization inhibition and lipid (hormone) binding [review]
Our results show that CSF (show CSF2 Antibodies) fetuin-A is a biomarker of disease activity and natalizumab response in multiple sclerosis
lipid-induced FetA from adipocytes is an efficient chemokine (show CCL1 Antibodies) for macrophage migration and polarization
FetA, via its terminal galactoside moiety, directly binds Leu100-Gly123 & Thr493-Thr516 in Tlr4 (show TLR4 Antibodies), fulfilling the requirement of an endogenous ligand for TLR4 (show TLR4 Antibodies) through which lipids induce insulin (show INS Antibodies) resistance.
Our results show that fetuin-A has a developmental rather than a structural role in murine bone.
Fetuin-A-containing calciprotein particles facilitate the clearance of mineral debris by macrophages via SR-A (show MSR1 Antibodies).
Fetuin-A was the only independent predictor for abnormal LAD (show ITGB2 Antibodies); mean arterial pressure was independently associated with concentric LVH, and age and hypoalbuminemia with eccentric LVH
Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure.
, 59 kDa bone sialic acid-containing protein
, alpha 2 HS-glycoprotein alpha 2 (fetuin)
, glycoprotein PP63
, phosphorylated N-glycoprotein pp63
, alpha-2-HS glycoprotein
, pre-pro polypeptide (AA -18 to -346)
, alpha2-HS glycoprotein