anti-delta-Like 1 Homolog (Drosophila) (DLK1) Antibodies

DLK1 encodes a transmembrane protein containing six epidermal growth factor repeats. Additionally we are shipping DLK1 Kits (27) and DLK1 Proteins (25) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DLK1 8788 P80370
DLK1 13386 Q09163
DLK1 114587  
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Top anti-DLK1 Antibodies at antibodies-online.com

Showing 10 out of 183 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-DLK1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Human Stomach 100 μL Log in to see 2 to 3 Days
$319.00
Details
Mouse Rabbit Un-conjugated FACS, SimWes, WB Detection of Mouse Pref-1/DLK1/FA1 by Western Blot. Western blot shows lysates of 3T3-L1 mouse embryonic fibroblast adipose-like cell line and mouse embryo tissue. PVDF membrane was probed with 1:1000 dilution of Rabbit Anti-Mouse Pref-1/DLK1/FA1 Monoclonal Antibody. This experiment was conducted under reducing conditions. Detection of Pref-1/DLK1/FA1 in 3T3-L1 Mouse Cell Line by Flow Cytometry. 3T3-L1 mouse embryonic fibroblast adipose-like cell line was stained with Rabbit Anti-Mouse Pref-1/DLK1/FA1 Monoclonal Antibody. 100 μL Log in to see 8 to 9 Days
$328.90
Details
Human Mouse Un-conjugated ELISA, FACS, ICC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using DLK1 mAb against human DLK1 (AA: 174-349) recombinant protein. (Expected MW is 44.9 kDa)  Dilution: 1/500 - 1/2000 100 μL Log in to see 8 to 11 Days
$561.00
Details
Human Mouse Un-conjugated ELISA, FACS 100 μL Log in to see 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using DLK1 antibody. 100 μL Log in to see 16 Days
$334.77
Details
Mouse Rabbit Alexa Fluor 488 FACS Detection of Pref-1/DLK1/FA1 in 3T3-L1 Mouse Cell Line by Flow Cytometry. 3T3-L1 mouse embryonic fibroblast adipose-like cell line was stained with Rabbit Anti-Mouse Pref-1/DLK1/FA1 Alexa Fluor 488-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$351.90
Details
Mouse Rabbit PE FACS Detection of Pref-1/DLK1/FA1 in 3T3-L1 Mouse Cell Line by Flow Cytometry. 3T3-L1 mouse embryonic fibroblast adipose-like cell line was stained with Rabbit Anti-Mouse Pref-1/DLK1/FA1 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$369.15
Details
Mouse Rabbit APC FACS Detection of Pref-1/DLK1/FA1 in 3T3-L1 Mouse Cell Line by Flow Cytometry. 3T3-L1 mouse embryonic fibroblast adipose-like cell line was stained with Rabbit Anti-Mouse Pref-1/DLK1/FA1 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$369.15
Details
Mouse Rat FITC FACS 100 μL Log in to see 11 to 13 Days
$680.80
Details
Mouse Rat Un-conjugated IHC (fro), FACS, IHC (p) 0.1 mg Log in to see 6 to 8 Days
$368.50
Details

Top referenced anti-DLK1 Antibodies

  1. Human Monoclonal DLK1 Primary Antibody for ICC, FACS - ABIN969086 : Espina, Méndez-Vidal, Moreno-Mateos, Sáez, Romero-Franco, Japón, Pintor-Toro: Induction of Dlk1 by PTTG1 inhibits adipocyte differentiation and correlates with malignant transformation. in Molecular biology of the cell 2009 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal DLK1 Primary Antibody for CyTOF, FACS - ABIN4899811 : Kim, Lin, Zelterman, Yun: Hypoxia-regulated delta-like 1 homologue enhances cancer cell stemness and tumorigenicity. in Cancer research 2009 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal DLK1 Primary Antibody for WB - ABIN522231 : Kilian, Beck-Sickinger: Recombinant expression and characterization of biologically active protein delta homolog 1. in Protein expression and purification 2015 (PubMed)

  4. Human Monoclonal DLK1 Primary Antibody for FACS, IHC - ABIN1169184 : Kluth, Radke, Kögler: Increased Haematopoietic Supportive Function of USSC from Umbilical Cord Blood Compared to CB MSC and Possible Role of DLK-1. in Stem cells international 2013 (PubMed)

  5. Human Polyclonal DLK1 Primary Antibody for FACS, IHC (p) - ABIN6243159 : Hu, Guan, Liu, Dai, Tang, Xiao, Qian, Sharrow, Ye, Wu, Xu: Endoglin Is Essential for the Maintenance of Self-Renewal and Chemoresistance in Renal Cancer Stem Cells. in Stem cell reports 2018 (PubMed)

  6. Mouse (Murine) Monoclonal DLK1 Primary Antibody for ELISA, WB - ABIN1169190 : Kim, Kang, Park, Kim, Park, Kim, Leem, Chu, Lee, Jho, Oh: Identification of a stroma-mediated Wnt/beta-catenin signal promoting self-renewal of hematopoietic stem cells in the stem cell niche. in Stem cells (Dayton, Ohio) 2009 (PubMed)

  7. Dog (Canine) Polyclonal DLK1 Primary Antibody for WB - ABIN2773880 : Zhou, Wang, Wang, Zhu, Shu, Liao, Yu, Gao, Xi, Wang, Zhang, Yuan, Jiang: Global comparison of gene expression profiles between intramuscular and subcutaneous adipocytes of neonatal landrace pig using microarray. in Meat science 2010 (PubMed)

More Antibodies against DLK1 Interaction Partners

Cow (Bovine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. DLK1 mRNA expression in mesenteric fat was higher than subcutaneous fat. DLK1 mRNA expression in Holstein cattle mesenteric fat was higher than Wagyu cattle.

  2. The four loci of DLK1 gene and CLPG gene in 1109 individuals, which belong to eight breeds/species of bovidae, including cattle, buffalo and yak, were analyzed.

  3. tissue-specific expression patterns of Dlk-1 splice variants in bovine tissues

Human delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. Data suggest that targeted methylation of MEG3 (show FAM129B Antibodies)-DMRs (differentially methylated regions) is sufficient to repress DLK1-MEG3 (show FAM129B Antibodies) locus and increase beta-cell susceptibility to cytokines; this study provides evidence for role of novel enhancer in regulation of imprinting at DLK1-MEG3 (show FAM129B Antibodies) locus in beta-cells of subjects with type 2 diabetes . (MEG3 (show FAM129B Antibodies) = MEG3 (show FAM129B Antibodies) non-coding RNA; DLK1 = delta-like 1 (show DLL1 Antibodies) protein)

  2. We conclude methylation changes at some CpG sites of MEST (show MEST Antibodies) and DLK (show DAPK3 Antibodies) differentially methylated regions in preeclamptic group

  3. point mutations in DLK1 and KCNK9 (show KCNK9 Antibodies) at least do not seem to be a common cause of central precocious puberty in girls.

  4. The expression of piRNAs encoded at DLK1-DIO3 (show DIO3 Antibodies) enhances the prognostic potential of small non-coding RNAs specific to this locus in predicting lung cancer patient outcome.

  5. targeting DLK1 might inhibit the tumor growth via initiating cell differentiation of hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cancer stem cell.

  6. SASH1 (show SASH1 Antibodies) acts through NOTCH1 (show NOTCH1 Antibodies) and its inhibitor DLK1 in a three-dimensional model of lumenogenesis involving CEACAM1 (show CEACAM1 Antibodies).

  7. The data presented in this work suggest that a fine regulation of NOTCH (show NOTCH1 Antibodies) signaling BY DLK1 plays an important role in the control of breast cancer cell proliferation and invasion.

  8. results demonstrate that miR (show MLXIP Antibodies)-129-5p inhibits non-small cell lung cancer stemness and chemoresistance through direct targeting of DLK1

  9. A complex defect of DLK1 ( approximately 14-kb deletion and 269-bp duplication) was identified in a family with central precocious puberty. This deletion included the 5' untranslated region and the first exon of DLK1, including the translational start site. Only family members who inherited the defect from their father have precocious puberty, consistent with the known imprinting of DLK1.

  10. Loss of DLK1 expression is associated with fetal growth retardation complications of pregnancy.

Pig (Porcine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. trans-associations occur between three imprinted genes IGF2, DLK1 and MEG3 both in fetal liver and muscle cells.

  2. We did not observe significantly different expression of DLK1, MEG3 or PEG11 (show RTL1 Antibodies) mRNA in any of analyzed breeds.

  3. QUASEP supports paternal expression of DLK1 in whole brain, carcass, liver and placental tissues of day 30 interbreed porcine fetuses.

  4. the sequence of porcine DLK1 (pDLK1)was examined,the expression and alternative splicing isoforms in the pig (Sus scrofa) was compared with human

  5. Polymorphisms, imprinting status and quantitative trait locus analyses of the porcine DLK1 and MEG3 genes i swine.

  6. Expression of DLK1 splice variants during adipocyte development in vitro and in vivo.

Mouse (Murine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. Functional analysis revealed that ground-state miRNAs embedded in the Dlk1-Dio3 (show DIO3 Antibodies) locus (miR (show MLXIP Antibodies)-541-5p, miR (show MLXIP Antibodies)-410-3p, and miR (show MLXIP Antibodies)-381-3p) promoted pluripotency via inhibition of multi-lineage differentiation and stimulation of self-renewal

  2. This study suggests that Pref-1 is an endocrine factor which is synergistically increased by obesity and age.

  3. Gene body methylation of noncoding RNA genes was observed and among these microRNA genes were prominent. Of particular note, observed only in hyperphenylalaninemic animals, was hypomethylation of miRNA genes within the imprinted Dlk1-Dio3 (show DIO3 Antibodies) locus on chromosome 12.

  4. The role of elevated oxygen levels in eroding imprinted Dlk1 expression during prolonged culture and in vitro differentiation.

  5. Loss of DLK1 expression is associated with fetal growth retardation complications of pregnancy.

  6. Pref-1 mRNA is a novel substrate of RNase-L (show RNASEL Antibodies).

  7. the conserved sequences in IG-DMR (show WDR20 Antibodies) are involved in the expression regulation of some of the imprinted genes in the Dlk1-Dio3 (show DIO3 Antibodies) domain

  8. To investigate the nature of these more variably methylated secondary differentially methylated regions, we adopted a hairpin linker bisulfite mutagenesis approach to examine CpG dyad methylation at differentially methylated regions associated with the murine Dlk1/Gtl2 imprinting cluster on both complementary strands.

  9. NOTCH1 (show NOTCH1 Antibodies) ligand Delta-like 1 (show DLL1 Antibodies) homolog (DLK1) self interacts

  10. the salivary gland phenotype of Dlk1 knock-out mice, was investigated.

DLK1 Antigen Profile

Protein Summary

This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes\; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance\; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

Gene names and symbols associated with DLK1

  • delta like non-canonical Notch ligand 1 (DLK1) antibody
  • delta-like 1 homolog (Drosophila) (DLK1) antibody
  • delta-like 1 homolog (Drosophila) (Dlk1) antibody
  • delta like non-canonical Notch ligand 1 (Dlk1) antibody
  • AW742678 antibody
  • Delta1 antibody
  • DLK antibody
  • DLK-1 antibody
  • DlkI antibody
  • FA1 antibody
  • Ly107 antibody
  • Peg9 antibody
  • pG2 antibody
  • pref-1 antibody
  • PREF1 antibody
  • SCP1 antibody
  • Zog antibody

Protein level used designations for DLK1

fetal antigen 1 , preadipocyte factor 1 , protein delta homolog 1 , secredeltin , delta-like homolog , preadipocyte factor-1 , delta-like 1 homolog (Drosophila) , delta-like protein 1 , protein delta homolog 1-like , adipocyte differentiation inhibitor protein , stromal cell derived protein 1

GENE ID SPECIES
8788 Homo sapiens
281117 Bos taurus
423459 Gallus gallus
490860 Canis lupus familiaris
497066 Sus scrofa
641301 Ovis aries
707595 Macaca mulatta
100054933 Equus caballus
100082485 Ornithorhynchus anatinus
100303692 Meleagris gallopavo
100449207 Pongo abelii
100598289 Nomascus leucogenys
13386 Mus musculus
114587 Rattus norvegicus
100349369 Oryctolagus cuniculus
100719185 Cavia porcellus
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