anti-gamma-Glutamylcyclotransferase (GGCT) Antibodies

The protein encoded by GGCT catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. Additionally we are shipping gamma-Glutamylcyclotransferase Proteins (13) and gamma-Glutamylcyclotransferase Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GGCT 110175 Q9D7X8
GGCT 362368  
GGCT 79017 O75223
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Top anti-gamma-Glutamylcyclotransferase Antibodies at antibodies-online.com

Showing 10 out of 66 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of GGCT Antibody (C-term) in 293 cell line lysates (35ug/lane). GGCT (arrow) was detected using the purified Pab. 0.4 mL 6 to 8 Days
$484.00
Details
Human Rabbit Un-conjugated ELISA, IHC (p), IP, WB Immunochemical staining of human GGCT in human lung cancer with rabbit polyclonal antibody (0.1 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of human GGCT in human hepatoma with rabbit polyclonal antibody (0.1 µg/mL, formalin-fixed paraffin embedded sections). 100 μL 14 to 16 Days
$247.82
Details
Human Rabbit Un-conjugated WB Western blot analysis of GGCT Antibody in 293 cell line lysates (35ug/lane) 400 μL 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of various cell lines, using GGCT antibody (ABIN1876220) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s. 100 μL 11 to 13 Days
$433.51
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Anti-GGCT antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100. 200 μL 11 to 14 Days
$484.00
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cell lines, using GGCT antibody (ABIN5972861) at 1/1000 dilution. 100 μL 11 to 16 Days
$426.40
Details
Human Rabbit Un-conjugated WB   100 μL 11 to 14 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA   100 μL 14 to 16 Days
$183.12
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of Lane 1: RT-4, Lane 2: U-251 MG, Lane 3: Human Plasma, Lane 4: Liver, Lane 5: Tonsil with GGCT polyclonal antibody . Immunohistochemical staining of human corpus, uterine with GGCT polyclonal antibody  shows moderate cytoplasmic positivity in glandular cells. 100 μL 11 to 12 Days
$577.33
Details

Top referenced anti-gamma-Glutamylcyclotransferase Antibodies

  1. Human Polyclonal GGCT Primary Antibody for IHC, IHC (p) - ABIN4313404 : Gromov, Gromova, Friis, Timmermans-Wielenga, Rank, Simon, Sauter, Moreira: Proteomic profiling of mammary carcinomas identifies C7orf24, a gamma-glutamyl cyclotransferase, as a potential cancer biomarker. in Journal of proteome research 2010 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal GGCT Primary Antibody for IHC, IHC (p) - ABIN4313405 : Amano, Eishi, Yamada, Uchida, Minegishi, Tamura, Kobayashi, Hiroshi, Suzuki, Board: Widespread expression of γ-glutamyl cyclotransferase suggests it is not a general tumor marker. in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2011 (PubMed)

More Antibodies against gamma-Glutamylcyclotransferase Interaction Partners

Human gamma-Glutamylcyclotransferase (GGCT) interaction partners

  1. GGCT is highly upregulated in HGSC tissues and associated with FIGO stage, lymph node metastasis and ascitic fluid volume. High expression of GGCT is associated with poor survival in HGSC patients.

  2. Taken together, the results indicate that PHB2 plays a central role in p21 upregulation following GGCT knockdown and as such may promote deregulated proliferation of cancer cells by suppressing p21.

  3. GGCT plays a critical role in glioma cell proliferation and may be a potential cancer therapeutic target.

  4. GGCT is promising as a diagnostic marker and a therapeutic target for various cancers. This review summarizes these interesting findings.

  5. G6PD, GGCT, IDH1, isocitrate dehydrogenase 2 (NADP+,mitochondrial) (IDH2) and glutathione S-transferase pi 1(GSTP1), five of the critical components of GSH pathway, contribute to chemoresistance.

  6. GGCT plays a critical role in lung cancer cell proliferation.

  7. Transcriptional silencing of the C7orf24 gene in the non-malignant cells is elicited through heterochromatin formation in its promoter region.

  8. increased expression of GGCT was a common event among invasive esophageal squamous cell carcinoma tissues regardless of the depth of invasion. Lymph node metastasis and tumor differentiation correlated with GGCT expression

  9. C7orf24 has been recognized as a potent marker for bladder and breast cancers. Studies on the role of gamma-glutamylcyclotransferace may aid in the control of malignant transformation of these cancers.

  10. GGCT may be a biomarker of tumors in a limited range of organs.

  11. C7orf24 overexpression defines a subgroup of breast tumors with poor clinical outcome.

  12. CRF21 might play an important role in the induction of apoptosis by GGO in leukemia U937 cells.

  13. presence of extra electron density/ligands and conservation at the sequence and structure levels, it is likely that the cavity has a crucial role in the function of LOC79017 and its structural neighbors possibly as an active site or ligand-binding site

  14. The GGCT gene is located on chromosome 7p14-15 and consists of four exons that span 8 kb, the primary sequence is 188 amino acids in length and is unlike any protein of known function

gamma-Glutamylcyclotransferase (GGCT) Antigen Profile

Protein Summary

The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with GGCT

  • gamma-glutamylcyclotransferase b (ggctb) antibody
  • gamma-glutamylcyclotransferase (GGCT) antibody
  • gamma-glutamylcyclotransferase (ggct) antibody
  • gamma-glutamyl cyclotransferase (ggct) antibody
  • gamma-glutamyl cyclotransferase (Ggct) antibody
  • A030007L17Rik antibody
  • AA673177 antibody
  • C7orf24 antibody
  • CRF21 antibody
  • fj35c05 antibody
  • GCTG antibody
  • GGC antibody
  • ggct antibody
  • Ggctl1 antibody
  • RGD1304876 antibody
  • RGD1562590 antibody
  • wu:fj35b07 antibody
  • wu:fj35c05 antibody
  • zgc:56140 antibody

Protein level used designations for GGCT

gamma-glutamylcyclotransferase , gamma-glutamyl cyclotransferase , gamma-glutamyl cyclotransferase-like 1 , cytochrome c-releasing factor 21 , gamma -glutamyl cyclotransferase

GENE ID SPECIES
406278 Danio rerio
463327 Pan troglodytes
611603 Canis lupus familiaris
613056 Xenopus (Silurana) tropicalis
695547 Macaca mulatta
100528263 Ictalurus punctatus
110175 Mus musculus
362368 Rattus norvegicus
79017 Homo sapiens
533374 Bos taurus
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