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ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009 [PubMed 19065146]).[supplied by OMIM, Apr 2010].. Additionally we are shipping ARHGAP18 Proteins (2) and and many more products for this protein.
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ARHGAP 18 was identified as a novel protective gene against thoracic aortic aneurysm formation.
In endothelial cells, ARHGAP18 may act as a significant regulator of vascular homeostasis.
Results describe ARHGAP18 as a novel negative regulator of sprouting by acting dualistically to limit tip cell formation and to maintain junctional integrity.
Our data suggest that ARHGAP18, which was located by the SNP rs11759328 via positive selection, plays a potential role in regulating HbF expression in beta-thalassaemia and may be a promising therapeutic target
these results define opposing roles for oncogenic ARHGAP18 and tumor suppressive miR (show MLXIP Antibodies)-200b in determining triple-negative breast cancer cell migration and metastatic prowess
data suggest the ARHGAP18 may confer vulnerability to SZ in the Chinese Han population, providing additional evidence for the involvement of neurodevelopmental dysfunction in the pathogenesis of schizophrenia
Our results show that miR (show MLXIP Antibodies)-181a is down-regulated in glioblastoma multiforme (GBM) patients. The three target genes, ANGPT2 (show ANGPT2 Antibodies), ARHGAP18 and LAMC1 (show LAMC1 Antibodies), are negatively correlated with the expression of miR (show MLXIP Antibodies)-181a. Moreover, high expression of ANGPT2 (show ANGPT2 Antibodies) or LAMC1 (show LAMC1 Antibodies) together with large size of GBM is correlated with a shorter median overall survival
The results define ARHGAP18 as one of the crucial factors for the regulation of RhoA (show RHOA Antibodies) for the control of cell shape, spreading, and migration.
identification of a novel gene, SENEX, that regulates stress induced premature senescence pathways in endothelial cells involving p16(INK4a) and retinoblastoma protein activation
This study use Functional MRI (show C7ORF49 Antibodies) and Genome Wide Association Analysis indentic novel gene(ARHGAP18) associated with schizophrenia.
ARHGAP18 belongs to a family of Rho (see MIM 165390) GTPase-activating proteins that modulate cell signaling (Potkin et al., 2009
rho GTPase-activating protein 18
, rho-type GTPase-activating protein 18
, Rho GTPase activating protein 18
, rho GTPase-activating protein 18-like