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ARHGAP22 encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins.
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Human Polyclonal ARHGAP22 Primary Antibody for ELISA, ICC - ABIN4281506
Aitsebaomo, Wennerberg, Der, Zhang, Kedar, Moser, Kingsley-Kallesen, Zeng, Patterson: p68RacGAP is a novel GTPase-activating protein that interacts with vascular endothelial zinc finger-1 and modulates endothelial cell capillary formation. in The Journal of biological chemistry 2004
There is a significant association between single nucleotide polymorphism in the ARHGAP22 gene and diabetic retinopathy risk in a Han Chinese population
a weak complex between RhoGAP protein (show ARHGAP26 Antibodies) ARHGAP22 and signal regulatory protein (show SIRPG Antibodies) 14-3-3 (show YWHAQ Antibodies) has 1 (show HAS1 Antibodies):2 stoichiometry and a single peptide binding mode
The interaction of the IL1RAPL1 (show IL1RAPL1 Antibodies) family of proteins with PTPdelta and RhoGAP2 reveals a pathophysiological mechanism of cognitive impairment associated with a novel type of trans-synaptic signaling.
Identification of RhoGAP22 as an Akt (show AKT1 Antibodies)-dependent regulator of cell motility in response to insulin (show INS Antibodies)
We identified a genetic association for susceptibility to retinopathy in 5 novel chromosomal regions and PLXDC2 (show PLXDC2 Antibodies) and ARHGAP22, the latter 2 of which are genes implicated in endothelial cell angiogenesis and increased capillary permeability.
a multifunctional regulatory protein (show TGFB1 Antibodies) with Rac1-specific GTPase (show RACGAP1 Antibodies)-activating activity; regulates transcriptional activity of the endothelin-1 (show EDN1 Antibodies) promoter; involved in the signal transduction pathway regulating endothelial cell capillary tube formation
This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene.
Rho GTPase activating protein 22
, Rho GTPase activating protein 2
, Rho GTPase activating protein 25-like
, rho GTPase-activating protein 22-like
, rho GTPase activating protein 22
, rho GTPase-activating protein 22
, rho-type GTPase-activating protein 22