ARHGAP22 antibody (C-Term)

Catalog No. ABIN6260025

Product Details anti-ARHGAP22 Antibody

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP22 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: ARHGAP22 Antibody detects endogenous levels of total ARHGAP22.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ARHGAP22, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for ARHGAP22

Target: ARHGAP22 (rho GTPase Activating Protein 22 (ARHGAP22))

Alternative Name: ARHGAP22 (ARHGAP22 Products)

Synonyms: si:ch211-223a10.2 antibody, RhoGAP2 antibody, RhoGap22 antibody, B230341L19Rik antibody, RHOGAP2 antibody, p68RacGAP antibody, Rho GTPase activating protein 22 antibody, rho GTPase activating protein 22 antibody, ARHGAP22 antibody, arhgap22 antibody, CC1G_06014 antibody, Arhgap22 antibody

Background:

Description: Rho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter (By similarity).

Gene: ARHGAP22

Molecular Weight: 77kDa

Gene ID: 58504

UniProt: Q7Z5H3