serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) ELISA Kits

The protein encoded by SPINK1 is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. Additionally we are shipping serine Peptidase Inhibitor, Kazal Type 1 Antibodies (79) and serine Peptidase Inhibitor, Kazal Type 1 Proteins (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SPINK1 6690 P00995
SPINK1 266602 P09656
Anti-Mouse SPINK1 SPINK1 20730 P09036
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Top serine Peptidase Inhibitor, Kazal Type 1 ELISA Kits at antibodies-online.com

Showing 6 out of 23 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.61 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests Log in to see 13 to 16 Days
$736.84
Details
Rat 1.95 ng/mL   96 Tests Log in to see 15 to 18 Days
$910.56
Details
Pig
0.78-50 ng/mL   96 Tests Log in to see 2 to 3 Days
$867.90
Details
Human < 0.63 ng/mL 1.56 ng/mL - 100 ng/mL   96 Tests Log in to see 11 to 18 Days
$810.17
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details
Dog
  96 Tests Log in to see 15 to 18 Days
$1,095.60
Details

Top referenced serine Peptidase Inhibitor, Kazal Type 1 ELISA Kits

  1. Human SPINK1 ELISA Kit for Sandwich ELISA - ABIN422754 : El-mezayen, Metwally, Darwish: A novel discriminant score based on tumor-associated trypsin inhibitor for accurate diagnosis of metastasis in patients with breast cancer. in Tumour biology 2014 (PubMed)

More ELISA Kits for serine Peptidase Inhibitor, Kazal Type 1 Interaction Partners

Human serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) interaction partners

  1. Data show that alteration in beta-catenin (show CTNNB1 ELISA Kits) expression, a core component of the CDH17/beta-catenin (show CTNNB1 ELISA Kits) axis, in tumors affects serine peptidase inhibitor Kazal type 1 (SPINK1) serum levels in hepatocellular carcinoma (HCC) patients.

  2. Findings indicate that the serine protease inhibitor, Kazal type 1 (SPINK1) p.N34S allele may cause reduced SPINK1 expression.

  3. Having correlated our findings with current knowledge of SPINK1's role in exocrine pancreas pathophysiology, we propose that complete and partial functional losses of the SPINK1 gene are associated with quite distinct phenotypes, the former causing a new pediatric disease entity of severe infantile isolated exocrine pancreatic insufficiency (EPI (show TFPI ELISA Kits)) .

  4. results suggest that rs142703147:C>A, which disrupts a PTF1L-binding site within an evolutionarily conserved HNF1A (show HNF1A ELISA Kits)-PTF1L cis-regulatory module located upstream of the SPINK1 promoter, contributes to the chronic pancreatitis risk haplotype.

  5. Studied mutations in cationic trypsinogen (PRSS1 (show PRSS1 ELISA Kits)) and serine protease inhibitor Kazal type 1 (SPINK1) and their association with alcoholic chronic pancreatitis (ACP) and idiopathic chronic pancreatitis.

  6. Studies indicate that serine peptidase inhibitor Kazal type 1 (SPINK1) gene, particularly the N34S mutation, has a genetic association with the development of pancreatitis [Meta-analysis].

  7. association between SPINK1 p.N34S gene variation and chronic pancreatitis [review, meta-analysis]

  8. We present the case of a child with a homozygous mutation N34S in the SPINK1 gene, leading to acute recurrent pancreatitis and ultimately to chronic pancreatitis

  9. Used in silico splicing prediction programs to prioritize SPINK1 intronic variants for further quantitative RT-PCR analysis the non-pathological c.194 + 13T > G variant was predicted by different programs to generate a new & viable donor splice site, the prediction scores being comparable to those for the physiological c.194 + 2T donor splice site & even higher than those for the physiological c.87 + 1G donor splice site.

  10. Gene mutations were present in PRSS1 (show PRSS1 ELISA Kits) in 26 patients with acute recurrent and chronic pancreatitis, SPINK1 in 23, CTRC (show CTRC ELISA Kits) in 3, and CPA1 (show CPA1 ELISA Kits) in 5. In the 31 patients with mutations in SPINK1, CTRC (show CTRC ELISA Kits), or CPA1 (show CPA1 ELISA Kits), 16 (51.6%) had homozygous or heterozygous mutations with other mutations.

Cow (Bovine) serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) interaction partners

  1. Partially folded bovine pancreatic trypsin inhibitor analogues attain fully native structures when co-crystallized with S195A rat trypsin.

Mouse (Murine) serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) interaction partners

  1. It is a trypsin-specific inhibitor in the pancreas.

  2. IFN regulatory factor 2 (Irf2 (show IRF2 ELISA Kits)) has a regulatory role in trypsinogen5 gene transcription, which is resistant to a major endogenous trypsin inhibitor, Spink3 (show SPINK3 ELISA Kits)

  3. SPINK3 modulates sperm physiology through a downstream reduction of endogenous NO concentration and independently of SPINK3 trypsin inhibitory activity.

  4. uterine-gland-derived SPINK3 (show SPINK3 ELISA Kits), as a new paracrine modulator, might play an important role in embryo implantation through its influence on stromal decidualization in mice.

  5. Spink3 (show SPINK3 ELISA Kits) may act as a growth factor, leading to cell proliferation and regeneration of tissue structure.

  6. Results suggest that regulation of Prss1 (show PRSS1 ELISA Kits) and Spink3 (show SPINK3 ELISA Kits) expression is involved in the susceptibility to experimentally induced pancreatitis.

  7. Spink3 (show SPINK3 ELISA Kits) trypsin inhibitor is required for normal pancreatic development. Data indicate an important relationship between endogenous pancreatic trypsin and Spink3 (show SPINK3 ELISA Kits) and the development of pancreatitis.

  8. SPINK3 (show SPINK3 ELISA Kits) mRNA is upregulated in chronic pancreatitis.

  9. Spink3 (show SPINK3 ELISA Kits) may play important roles in proliferation and/or differentiation of various cell types during development.

serine Peptidase Inhibitor, Kazal Type 1 (SPINK1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a trypsin inhibitor, which is secreted from pancreatic acinar cells into pancreatic juice. It is thought to function in the prevention of trypsin-catalyzed premature activation of zymogens within the pancreas and the pancreatic duct. Mutations in this gene are associated with hereditary pancreatitis and tropical calcific pancreatitis.

Gene names and symbols associated with SPINK1

  • serine peptidase inhibitor, Kazal type 1 (SPINK1) antibody
  • serine peptidase inhibitor, Kazal type 1 (Spink1) antibody
  • p12 antibody
  • PCTT antibody
  • Psti antibody
  • SPINK1 antibody
  • Spink3 antibody
  • TATI antibody
  • TCP antibody

Protein level used designations for SPINK1

pancreatic secretory trypsin inhibitor , serine protease inhibitor Kazal-type 1 , serine protease inhibitor, Kazal type 1 , tumor-associated trypsin inhibitor , PSTI-II , calcium transport inhibitor , caltrin , pancreatic secretory trypsin inhibitor II , pancreatic secretory trypsin inhibitor type II (PSTI-II) , serine peptidase inhibitor, Kazal type 3 , serine protease inhibitor Kazal-type 3 , serine protease inhibitor, Kazal type 3 , serine peptidase inhibitor, Kazal type 1 , prostatic secretory glycoprotein

GENE ID SPECIES
6690 Homo sapiens
266602 Rattus norvegicus
574092 Bos taurus
740785 Pan troglodytes
100622575 Sus scrofa
20730 Mus musculus
608433 Canis lupus familiaris
101115618 Ovis aries
103347911 Oryctolagus cuniculus
100630883 Equus caballus
708951 Macaca mulatta
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