serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) ELISA Kits

SERPINE2 encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Additionally we are shipping SERPINE2 Antibodies (140) and SERPINE2 Proteins (19) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SERPINE2 5270 P07093
SERPINE2 29366 P07092
SERPINE2 20720 Q07235
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Top SERPINE2 ELISA Kits at antibodies-online.com

Showing 3 out of 27 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.078 ng/mL 0.312-20 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$788.33
Details
Rat 0.078 ng/mL 0.313-20 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$788.33
Details
Mouse 0.78 pg/mL 3.12-200 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details

Top referenced SERPINE2 ELISA Kits

  1. Rat (Rattus) SERPINE2 ELISA Kit for Sandwich ELISA - ABIN4993465 : Li, Zhao, Guo, Li, Qili, Xu, Qian, Liang, E, Chege Gitau, Wang, Huangfu, Wu, Xu, Shan: Overexpression of SerpinE2/protease nexin-1 Contribute to Pathological Cardiac Fibrosis via increasing Collagen Deposition. in Scientific reports 2018 (PubMed)

  2. Human SERPINE2 ELISA Kit for Sandwich ELISA - ABIN419070 : Wu, Liu, Duan, Gao, Li, Wang, Song, Shao, Yang, Yang: The Involvement of Protease Nexin-1 (PN1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration. in Scientific reports 2016 (PubMed)

More ELISA Kits for SERPINE2 Interaction Partners

Human serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. High SERPINE2 expression promotes vascular mimicry of breast cancer.

  2. Study identified a secreted protein, SerpinE2 or glia-derived nexin, as causative for the highly invasive potential of slow-cycling melanoma cells.

  3. miR-199a-3p overexpression inhibited the expression of the extracellular serine protease inhibitor E2 (SerpinE2).

  4. The role of PN-1 in the pathogenesis of intervertebral disk degeneration

  5. PN-1 and PEDF share structural and functional features, and expression patterns in the retina.

  6. SerpinE2 is required in the extracellular milieu of breast tumors where it acts in multiple ways to regulate tumor matrix deposition, thereby controlling tumor cell dissemination.

  7. Single nucleotide polymorphisms in EPHX1, GSTP1, SERPINE2, and TGFB1 contributing to the quantitative traits of chronic obstructive pulmonary disease in Chinese Han population.

  8. high expression of SerpinE2 in osteosarcoma stimulates cell proliferation, promotes drugresistance, and results in poor survival by regulating CDK4 and cyclin D1.

  9. The results indicate that SERPINE2 and SLPI play a significant role in the development of papillary thyroid cancer and imply that the evaluation of serum concentrations of both anticoagulant molecules may be considered as additional marker for the differentiation of malignancies during the preoperative diagnosis of patients with thyroid gland tumors.

  10. We filtered four OSCC genes including SERPINB9, SERPINE2, GAK, and HSP90B1 through the gene global prioritization score (P < 0.005).

  11. together, these data demonstrate that SERPINE2 might prevent cartilage catabolism by inhibiting the expression of MMP-13, one of the most relevant collagenases, involved in cartilage breakdown in OA.

  12. The results suggest that the rs3795879 polymorphism of SERPINE2 is not a risk factor for chronic obstructive pulmonary disease.

  13. aberrant Serpine2/Pn-1 is required for proliferation of human and mouse medulloblastoma cells.

  14. Our findings indicate that upregulated SERPINE2 may contribute to the aggressive phenotype of gastric cancer and suggest that SERPINE2 can be used as a novel prognostic factor and anticancer target in patients with gastric cancer.

  15. MAGI2, SERPINE2, and NT5C3B expression levels are associated with airway wall thickening and additionally with bronchial inflammation, emphysema, and lung function, respectively, all features of chronic obstructive pulmonary disease.

  16. Haplotypes carrying major alleles of rs729631 (C), rs975278 (G), rs7583463 (C) of SERPINE2 had protective effect on lung function amongst South Indian male smokers with COPD.

  17. role in lung homeostasis and pulmonary fibrosis

  18. SERPINE2 and PLAU are involved in cumulus expansion and oocyte maturation.

  19. Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 maturation and endothelial protein C receptor shedding via furin inhibition.

  20. Studies suggest that protease nexin 1 as a marker of prostate cancer.

Cow (Bovine) serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. stage-dependent regulation of granulosa cell PA and SerpinE2 production, consistent with a role in extracellular matrix remodeling during follicle growth.

  2. SERPINE2 is involved in the regulation of atresia in bovine follicles

  3. SERPINE2 expression is dynamically regulated in granulosa cells during dominant follicle development

Rhesus Monkey serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. Prostasin may be involved in follicular development, ovulation, and CL formation, whereas PN-1 may be present to regulate the proteolysis in these processes.[prostasin; protease nexin-1]

Mouse (Murine) serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 2 (SERPINE2) interaction partners

  1. PN-1 and PEDF share structural and functional features, and expression patterns in the retina.

  2. SerpinE2 is required in the extracellular milieu of breast tumors where it acts in multiple ways to regulate tumor matrix deposition, thereby controlling tumor cell dissemination.

  3. These data uncover a novel mechanism whereby loss of serine protease inhibition leads to lung lymphocyte accumulation.

  4. the involvement of PAI-1 in HIF-1-enhanced thrombosis and that an additional factor participates in regulating Pai-1 expression in compressed skin.

  5. aberrant Serpine2/Pn-1 is required for proliferation of human and mouse medulloblastoma cells.

  6. PN-1 strongly limits physiological angiogenesis.

  7. The PAI-1 inhibitor not only accelerated the expansion of the donor HSCs during the early-stage of regeneration, but also supported long-term hematopoiesis.

  8. a novel inhibitory interaction between CAP1/Prss8 and nexin-1, opening the search for specific CAP1/Prss8 antagonists that are independent of its catalytic activity

  9. SERPINE2 and PLAU are involved in cumulus expansion and oocyte maturation.

  10. Endothelial protease nexin-1 is a novel regulator of A disintegrin and metalloproteinase 17 maturation and endothelial protein C receptor shedding via furin inhibition.

  11. PN1 regulates Hh signaling by decreasing protein levels of the Hh ligand Sonic (SHH) and its downstream effectors.

  12. PN-1 has direct antiangiogenic properties and is a yet-unrecognized player in the angiogenic balance

  13. SERPINE2 protein may play a role as a sperm decapacitation factor.

  14. platelet PN-1 can be considered as a new important regulator of thrombolysis in vivo

  15. SERPINE2 is a major plasminogen activator(PA) inhibitor in the placenta and uterus during the estrous cycle, pregnancy, and lactation. It may participate in the PA-modulated tissue remodeling process in the mouse placenta and uterus.

  16. Data suggest that lack of extinction in protease nexin-1 KO mice is associated with changes in neuronal activity in the circuitry of the basal and central amygdaloid nuclei, supporting a differential impact on fear extinction in these areas.

  17. Platelet PN-1 is a key player in the thrombotic process, whose negative regulatory role has been, up to now, markedly underestimated.

  18. PN-1 may have a role in regulating activities of muscle proteases

  19. We report that brain proteolytic activity was strongly regulated by neuronal activity, with PN-1 being a major controlling element.

  20. p65 binds to the kappaB-like DNA sequence located at approximately -9 kbp in the SerpinE2

SERPINE2 Antigen Profile

Antigen Summary

This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. Thrombin, urokinase, plasmin and trypsin are among the proteases that this family member can inhibit. This gene is a susceptibility gene for chronic obstructive pulmonary disease and for emphysema. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SERPINE2

  • serpin family E member 2 (SERPINE2) antibody
  • serpin family E member 2 (serpine2) antibody
  • serpin family E member 2 (Serpine2) antibody
  • serine (or cysteine) peptidase inhibitor, clade E, member 2 (Serpine2) antibody
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 (serpine2) antibody
  • B230326M24Rik antibody
  • GDN antibody
  • GDNPF antibody
  • Gdnpn1 antibody
  • MGC143011 antibody
  • PAI-1 antibody
  • PI-7 antibody
  • PI7 antibody
  • Pn-1 antibody
  • PN1 antibody
  • PNI antibody
  • SERPINE2 antibody
  • Spi4 antibody
  • Spin4 antibody
  • zgc:55929 antibody

Protein level used designations for SERPINE2

glia-derived nexin , glial-derived neurite promoting factor , peptidase inhibitor 7 , protease nexin I , serpin E2 , plasminogen activator inhibitor type 1, member 2 , serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 , serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 , protease nexin-1 , glia-derived nexin-like , GDN , Glia-derived nexin/protease nexin I , plasminogen activator inhibitor type 1 , protease nexin 1 , protease nexin PN-1 , serine (or cysteine) peptidase inhibitor, clade E, member 2 , serine (or cysteine) proteinase inhibitor, clade E, member 2 , serine protease inhibitor 4 , serpin peptidase inhibitor, clade E, member 2 , serine protease-inhibitor 4

GENE ID SPECIES
5270 Homo sapiens
282521 Bos taurus
459980 Pan troglodytes
608930 Canis lupus familiaris
707121 Macaca mulatta
100411540 Callithrix jacchus
100559583 Anolis carolinensis
100596009 Nomascus leucogenys
29366 Rattus norvegicus
20720 Mus musculus
100718082 Cavia porcellus
393153 Danio rerio
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