serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) ELISA Kits

The protein encoded by SERPINF1 is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. Additionally we are shipping serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Antibodies (149) and serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Proteins (57) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SERPINF1 5176 P36955
SERPINF1 20317 P97298
SERPINF1 287526  
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Top serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 ELISA Kits at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Delivery Price Details
Human 0.065 0.15 96 Tests 13 to 16 Days
$700.00
Details
Mouse 0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$720.00
Details
Rat 0.062 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 to 16 Days
$760.00
Details
Cow 0.135 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 to 16 Days
$840.00
Details
Pig 0.025 ng/mL 0.05-10 ng/mL Typical standard curve 96 Tests 13 to 16 Days
$788.33
Details
Human 0.6 0.6 96 Tests 2 to 3 Days
$480.70
Details
Rabbit 250 pg/mL 500-8000 pg/mL Typical standard curve 96 Tests 13 to 16 Days
$788.33
Details
Guinea Pig 1.0 ng/mL 5.0-100 ng/mL   96 Tests 15 to 18 Days
$707.14
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests 12 to 14 Days
$715.00
Details
Monkey 1.0 ng/mL 5.0-100 ng/mL   96 Tests 15 to 18 Days
$707.14
Details

Top referenced serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 ELISA Kits

  1. Rat (Rattus) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN367530 : Ozdemir, K?l?nç, Ergün, Sahin: Rapamycin inhibits oxidative and angiogenic mediators in diabetic retinopathy. in Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2014 (PubMed)
    Show all 10 Pubmed References

  2. Human SERPINF1 ELISA Kit for Sandwich ELISA - ABIN415117 : Hou, Liang, Wang, Zhang, Wang, Shi, Dong, Cai: A therapeutic strategy for choroidal neovascularization based on recruitment of mesenchymal stem cells to the sites of lesions. in Molecular therapy : the journal of the American Society of Gene Therapy 2010 (PubMed)
    Show all 6 Pubmed References

  3. Mouse (Murine) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN415701 : Liang, Hou, Yi, Yang, Gu, Lau, Gao, Ma, Lu, Wei, Pei, Yi: Increased expression of pigment epithelium-derived factor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injury. in European heart journal 2013 (PubMed)
    Show all 5 Pubmed References

  4. Mouse (Murine) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN367401 : Dai, Qi, Li, Lu, Mao, Yao, Li, Zhang, Hong, Li, Zhou, Yang, Yang, Gao, Cai: Dual regulation of adipose triglyceride lipase by pigment epithelium-derived factor: a novel mechanistic insight into progressive obesity. in Molecular and cellular endocrinology 2013 (PubMed)
    Show all 3 Pubmed References

  5. Human SERPINF1 ELISA Kit for Sandwich ELISA - ABIN365756 : Abu El-Asrar, Imtiaz Nawaz, Kangave, Siddiquei, Geboes: Osteopontin and other regulators of angiogenesis and fibrogenesis in the vitreous from patients with proliferative vitreoretinal disorders. in Mediators of inflammation 2012 (PubMed)
    Show all 2 Pubmed References

  6. Rat (Rattus) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN432444 : Yang, Luo, Zhou, Lv, Liu, Zhang, Gao, Chen, Xia, Luo, Cheng, Li: Rosiglitazone inhibits expression and secretion of PEDF in adipose tissue and liver of male SD rats via a PPAR-? independent mechanism. in Endocrinology 2014 (PubMed)

More ELISA Kits for serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Interaction Partners

Human serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. a novel dominant variant of COL1A1 likely underlies the severe foetal pathology observed, although we do not exclude the possibility that the heterozygous mutations in SERPINF and COL1A1 may interact and co-ordinately cause pathogenesis. This novel COL1A1 mutation is recommended to be included in the diagnostic panels for OI.

  2. Cancer-associated fibroblasts augment lipid storage and amplify centrosomal or non-centrosomal microtubule-organizing centers (MTOCs) through a PEDF-dependent lipid-MTOC signaling axis.

  3. findings demonstrate for the first time that PEDF negatively regulates Abeta42 and that PEDF deficiency with aging might play a crucial role in the development of Alzheimer's disease

  4. PEDF decreases the metastatic potential of non-small cell lung carcinoma cells through regulation of THBS1 release in cancer cell-derived exosomes.

  5. Low PEDF expression is associated with bladder cancer proliferation and invasion.

  6. Study does not support a pathogenic role for variants in SERPINF1 as a cause of otosclerosis after DNA resequencing of a large unrelated cohort of patients and 62 large otosclerosis families.

  7. ShRNA targeting HIF-1alpha can effectively silence the expression of HIF-1alpha, reduce the expression of VEGF and up-regulate the expression of PEDF in human corneal epithelial cells

  8. PEDF was demonstrated to increase UCP2 gene expression in ARPE19 cells.

  9. TGF-beta suppresses angiogenesis in systemic sclerosis, through decreased fibroblast Cav-1 expression and subsequent PEDF secretion

  10. In this review, we will summarize the role of PEDF in the development of atherosclerosis, focusing on endothelial dysfunction, inflammation, oxidative stress, angiogenesis and cell proliferation. We will also discuss its promising therapeutic implications for atherosclerosis.

  11. Pigment epithelium-derived factor's actions in osteoid tissues include promoting mesenchymal stem cell commitment to osteoblasts, increasing matrix mineralisation, and promoting osteoblast proliferation.

  12. Findings confirm that both M1- and M2-like macrophages are essential for retinal neovascularization and uncover a vital protective role of PEDF against retinal neovascularization by regulating macrophage recruitment and polarization.

  13. results suggest that PEDF act as a multipotent factor in the skin and the imbalance of PEDF and VEGF may be responsible for the transformation from normal skin to psoriasis.

  14. expression unaltered in preterm prelabor rupture of the membranes (pRPOM) or after exposure to risk factors of pPROM

  15. Data found novel mutations of the SERPINF1 and FKBP10 genes in Chinese families with autosomal recessive osteogenesis imperfecta

  16. Study showed that plasma PEDF levels were significantly lower in CAD patients than in controls.

  17. The T-C haplotype frequency of rs1136287-rs1894286 in PEDF were significantly correlated to the increased susceptibility to age-related macular degeneration(AMD). The rs1136287 polymorphism in PEDF may be related to the occurrence risk of AMD. Additionally, a haplotype is also a non-ignorable risk factor.

  18. this study is the first to demonstrate that PEDF promotes HUCMSC proliferation and protects them from apoptosis by reducing p53 expression in the serum-free medium. This study provides crucial information for clinical-scale expansion of human umbilical cord mesenchymal stem cells .

  19. Results show that the levels of miR-9, PEDF and VEGF are increased with diabetic nephropathy (DN) progression. miR-9, VEGF and PEDF are independent risk factors of DN.

  20. Results suggested that the pigment epithelium-derived factor (PEDF)/vascular endothelial growth factor (VEGF) ratio played a pivotal role in the spontaneous regression of infantile hemangioma (IH).

Pig (Porcine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. After cryotherapy of the sclera, pigment epithelium-derived factor levels increased 44.8% compared to untreated controlsand stayed at that level until day 14. It returned to baseline by day 21. (untreated).

  2. the inhibitory effect of PEDF appears to be mediated via the processing of VEGF-R2 by gamma-secretase

Cow (Bovine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. PEDF inhibits key steps in the angiogenic response of retinal capillary endothelial cells, including cell proliferation and vascular tubule formation. Gene expression of PEDF is negatively regulated by glucose, insulin (via mTOR) and VEGF.

  2. Results suggest that leptin might elicit angiogenesis through vascular endothelial growth factor induction as well as pigment epithelium-derived factor suppression in pericytes.

  3. PEDF promotes growth of pericytes through autocrine production of PDGFB.

  4. PEDF and VEGFR-1 have roles in the negative regulation of angiogenesis

Horse (Equine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. data suggest that PEDF, via its potent antiangiogenic capabilities, may contribute to superior healing in wounds on the trunks of horses by protecting from excessive formation of vascular granulation tissue

Mouse (Murine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. The findings reveal rescue from death of degenerating photoreceptor cells by a PEDF-mediated preservation of intracellular calcium homeostasis.

  2. our findings demonstrate for the first time that PEDF negatively regulates Abeta42 and that PEDF deficiency with aging might play a crucial role in the development of Alzheimer's disease

  3. The results demonstrate that loss of PEDF (PEDF(-/-) mice) causes a distinctive wound healing phenotype that is characterized by increased angiogenesis and delayed resolution.

  4. PEDF knockout mice exhibit normal hematopoiesis.

  5. PEDF expression has a significant impact on oxidative and inflammatory properties of choroidal endothelial cells, whose alteration could contribute to pathogenesis of chronic inflammatory diseases including exudative age-related macular degeneration.

  6. alpha2-antiplasmin increases brain MMP-9 levels during thromboembolic ischemic stroke in a dose-dependent fashion suggesting a mechanistic link. Results show that MMP-9 is essential for many of the harmful effects of alpha2-antiplasmin in promoting blood-brain barrier breakdown, swelling, hemorrhage and ischemic brain injury.

  7. TGF-beta suppresses angiogenesis in systemic sclerosis through decreased fibroblast Cav-1 expression and subsequent PEDF secretion.

  8. Loss of PEDF leads to ovarian oxidative damage accompanied by diminished ovarian reserve in mice, this is related to PEDF deficiency induced severe insulin resistance and lipid metabolism disorder.

  9. PN-1 and PEDF share structural and functional features, and expression patterns in the retina.

  10. The findings indicate that PEDF functions as a tumor-suppressor gene in the occurrence of epithelial-mesenchymal transition and metastasis in nasopharyngeal carcinoma.

  11. Expression of GLUT1 is stimulated by hyperglycemia and low oxygen supply, and this overexpression was associated with increased activity of GLUT1 in the cell membrane that contributes to the impairment of the RPE secretory function of PEDF.

  12. Combination of neuroprotective factors Pedf plus docosahexaenoic acid (DHA) stimulates corneal nerve regeneration. Data suggest activation of Pedfr by Pedf (here, applied topically to treat corneal nerve injury) promotes regeneration of corneal nerve via up-regulation of release of DHA (here, also applied topically) and expression of specific nerve tissue/eye proteins. (Pedfr = pigment epithelium-derived factor receptor)

  13. The renoprotective effects of PEDF are mediated, at least partially, by inhibition of the Wnt pathway in kidneys.

  14. PEDF deficiency has a significant impact on retinal endothelial cell adhesion and migration through altered production of extracellular matrix and junctional proteins in response to increased oxidative stress affecting their proangiogenic activity.

  15. PEDF is a hormone-regulated negative autocrine mediator of endometrial proliferation.

  16. These results indicate that PEDF counters Wnt signaling to allow for osteoblast differentiation and provides a mechanistic insight into how the PEDF null state results in OI type VI.

  17. Furthermore, pigment epithelium-derived factor (PEDF), a secreted glycoprotein known for its anti-tumor properties, blocked Wnt3a-directed induction of autophagy proteins. Autophagy inhibition was complemented by reciprocal regulation of the oxidative stress enzymes, superoxide dismutase 2 (SOD2) and catalase.

  18. Study demonstrated the inhibitory effect of PEDF on insulin-dependent molecular mechanisms of glucose homeostasis, and suggests that PEDF could be a specific target in the management of metabolic disorders.

  19. Alpha-2-Antiplasmin mediated myofibroblast formation and the development of renal fibrosis in unilateral ureteral obstruction via induction of TGF-beta.

  20. PEDF inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids in diabetic retinopathy.

serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.

Gene names and symbols associated with SERPINF1

  • serpin family F member 1 (SERPINF1) antibody
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (serpinf1) antibody
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 L homeolog (serpinf1.L) antibody
  • serpin family F member 1 (Serpinf1) antibody
  • serine (or cysteine) peptidase inhibitor, clade F, member 1 (Serpinf1) antibody
  • AI195227 antibody
  • Dmrs91 antibody
  • EPC-1 antibody
  • MGC82984 antibody
  • OI6 antibody
  • OI12 antibody
  • Pedf antibody
  • Pedfl antibody
  • Sdf3 antibody
  • SERPINF1 antibody
  • zgc:92072 antibody

Protein level used designations for SERPINF1

cell proliferation-inducing gene 35 protein , pigment epithelium-derived factor , serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 , serpin F1 , alpha-2 antiplasmin , pigment epithelium derived factor , serpin peptidase inhibitor, clade F, member 1 , serpin-F1 , serine (or cysteine) proteinase inhibitor, clade F), member 1 , serine (or cysteine) proteinase inhibitor, clade F, member 1 , serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 , alpha-2 antiplasmin, pigment epithelium derived factor , pigment epithelium-derived factor-like , SDF-3 , caspin , stromal cell derived factor 3 , stromal cell-derived factor 3 , serine (or cysteine) peptidase inhibitor, clade F, member 1

GENE ID SPECIES
5176 Homo sapiens
780402 Sus scrofa
281386 Bos taurus
394686 Xenopus (Silurana) tropicalis
417561 Gallus gallus
444412 Xenopus laevis
468137 Pan troglodytes
611276 Canis lupus familiaris
100072415 Equus caballus
100192425 Ovis aries
100216362 Cavia porcellus
100403187 Callithrix jacchus
100457889 Pongo abelii
100482247 Ailuropoda melanoleuca
100580793 Nomascus leucogenys
20317 Mus musculus
287526 Rattus norvegicus
447800 Danio rerio
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