serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) ELISA Kits

The protein encoded by SERPINF1 is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. Additionally we are shipping serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Antibodies (168) and serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Proteins (56) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SERPINF1 5176 P36955
SERPINF1 20317 P97298
SERPINF1 287526  
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Top serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 ELISA Kits at antibodies-online.com

Showing 10 out of 83 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.065 0.15 96 Tests Log in to see 13 to 16 Days
$560.00
Details
Mouse 0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$576.00
Details
Rat 0.062 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Log in to see 13 to 16 Days
$608.00
Details
Cow 0.135 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests Log in to see 13 to 16 Days
$672.00
Details
Pig 0.025 ng/mL 0.05-10 ng/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,107.33
Details
Human 0.6 0.6 96 Tests Log in to see 2 to 3 Days
$480.70
Details
Rabbit 250 pg/mL 500-8000 pg/mL Typical standard curve 96 Tests Log in to see 13 to 16 Days
$1,081.67
Details
Guinea Pig 1.0 ng/mL 5.0-100 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Chicken 0.938 ng/mL 1.563-100 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 1.0 ng/mL 5.0-100 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 ELISA Kits

  1. Human SERPINF1 ELISA Kit for Sandwich ELISA - ABIN415117 : Hou, Liang, Wang, Zhang, Wang, Shi, Dong, Cai: A therapeutic strategy for choroidal neovascularization based on recruitment of mesenchymal stem cells to the sites of lesions. in Molecular therapy : the journal of the American Society of Gene Therapy 2010 (PubMed)
    Show all 6 Pubmed References

  2. Rat (Rattus) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN367530 : Ozdemir, K?l?nç, Ergün, Sahin: Rapamycin inhibits oxidative and angiogenic mediators in diabetic retinopathy. in Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 2014 (PubMed)
    Show all 6 Pubmed References

  3. Mouse (Murine) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN415701 : Liang, Hou, Yi, Yang, Gu, Lau, Gao, Ma, Lu, Wei, Pei, Yi: Increased expression of pigment epithelium-derived factor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injury. in European heart journal 2013 (PubMed)
    Show all 5 Pubmed References

  4. Mouse (Murine) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN367401 : Dai, Qi, Li, Lu, Mao, Yao, Li, Zhang, Hong, Li, Zhou, Yang, Yang, Gao, Cai: Dual regulation of adipose triglyceride lipase by pigment epithelium-derived factor: a novel mechanistic insight into progressive obesity. in Molecular and cellular endocrinology 2013 (PubMed)
    Show all 3 Pubmed References

  5. Human SERPINF1 ELISA Kit for Sandwich ELISA - ABIN365756 : Abu El-Asrar, Imtiaz Nawaz, Kangave, Siddiquei, Geboes: Osteopontin and other regulators of angiogenesis and fibrogenesis in the vitreous from patients with proliferative vitreoretinal disorders. in Mediators of inflammation 2012 (PubMed)
    Show all 2 Pubmed References

  6. Rat (Rattus) SERPINF1 ELISA Kit for Sandwich ELISA - ABIN432444 : Yang, Luo, Zhou, Lv, Liu, Zhang, Gao, Chen, Xia, Luo, Cheng, Li: Rosiglitazone inhibits expression and secretion of PEDF in adipose tissue and liver of male SD rats via a PPAR-? independent mechanism. in Endocrinology 2014 (PubMed)

More ELISA Kits for serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Interaction Partners

Human serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. the trophoblast-derived anti-angiogenic molecule PEDF is involved in restricting growth and expansion of the feto-placental endothelium predominantly in late pregnancy and targets to modulate the intracellular effect of VEGF

  2. Mutations in SERPINF1 result in osteogenesis imperfecta (show COL1A2 ELISA Kits) Type VI

  3. Expression of GLUT1 (show SLC2A1 ELISA Kits) is stimulated by hyperglycemia and low oxygen supply, and this overexpression was associated with increased activity of GLUT1 (show SLC2A1 ELISA Kits) in the cell membrane that contributes to the impairment of the RPE secretory function of PEDF.

  4. Serum levels of PEDF were significantly correlated with body mass index, vasodilation and brachial artery intima-media thickness.

  5. PEDF expression in retinal endothelial cells plays a key role in modulation of cell proliferation, migration, and capillary morphogenesis.

  6. study found that PEDF binds to the C1q head regions and activates the classical complement pathway; in addition, observed that in synovial fluid (SF) from rheumatoid arthritis patients, PEDF forms detectable complexes with C4d, which are present in a range of concentrations; SF from nonarthritic donors consistently contained little or no C4d-PEDF complexes

  7. PEDF is a hormone-regulated negative autocrine mediator of endometrial proliferation.

  8. Findings suggest that PEDF plays a critical role in preventing hypoxia/reoxygenation injury by modulating anti-oxidant and anti-apoptotic factors and promoting autophagy.

  9. PEDF is associated with increased epithelial-mesenchymal transition in bladder cancer

  10. Six rare heterozygous SERPINF1 variants were found in seven patients in our familial otosclerosis cohort; three are missense mutations predicted to be deleterious to protein function

Pig (Porcine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. After cryotherapy of the sclera, pigment epithelium-derived factor levels increased 44.8% compared to untreated controlsand stayed at that level until day 14. It returned to baseline by day 21. (untreated).

  2. the inhibitory effect of PEDF appears to be mediated via the processing of VEGF-R2 by gamma-secretase

Cow (Bovine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. PEDF inhibits key steps in the angiogenic response of retinal capillary endothelial cells, including cell proliferation and vascular tubule formation. Gene expression of PEDF is negatively regulated by glucose, insulin (via mTOR) and VEGF.

  2. Results suggest that leptin (show LEP ELISA Kits) might elicit angiogenesis through vascular endothelial growth factor induction as well as pigment epithelium-derived factor suppression in pericytes.

  3. PEDF promotes growth of pericytes through autocrine production of PDGFB.

  4. PEDF and VEGFR-1 (show FLT1 ELISA Kits) have roles in the negative regulation of angiogenesis

Horse (Equine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. data suggest that PEDF, via its potent antiangiogenic capabilities, may contribute to superior healing in wounds on the trunks of horses by protecting from excessive formation of vascular granulation tissue

Mouse (Murine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. Expression of GLUT1 (show SLC2A1 ELISA Kits) is stimulated by hyperglycemia and low oxygen supply, and this overexpression was associated with increased activity of GLUT1 (show SLC2A1 ELISA Kits) in the cell membrane that contributes to the impairment of the RPE secretory function of PEDF.

  2. Combination of neuroprotective factors Pedf plus docosahexaenoic acid (DHA) stimulates corneal nerve regeneration. Data suggest activation of Pedfr by Pedf (here, applied topically to treat corneal nerve injury) promotes regeneration of corneal nerve via up-regulation of release of DHA (here, also applied topically) and expression of specific nerve tissue/eye proteins. (Pedfr = pigment epithelium-derived factor receptor)

  3. The renoprotective effects of PEDF are mediated, at least partially, by inhibition of the Wnt (show WNT2 ELISA Kits) pathway in kidneys.

  4. PEDF deficiency has a significant impact on retinal endothelial cell adhesion and migration through altered production of extracellular matrix and junctional proteins in response to increased oxidative stress affecting their proangiogenic activity.

  5. PEDF is a hormone-regulated negative autocrine mediator of endometrial proliferation.

  6. These results indicate that PEDF counters Wnt (show WNT2 ELISA Kits) signaling to allow for osteoblast differentiation and provides a mechanistic insight into how the PEDF null state results in OI type VI.

  7. Furthermore, pigment epithelium-derived factor (PEDF), a secreted glycoprotein known for its anti-tumor properties, blocked Wnt3a (show WNT3A ELISA Kits)-directed induction of autophagy proteins. Autophagy inhibition was complemented by reciprocal regulation of the oxidative stress enzymes, superoxide dismutase 2 (SOD2 (show SOD2 ELISA Kits)) and catalase (show CAT ELISA Kits).

  8. Study demonstrated the inhibitory effect of PEDF on insulin (show INS ELISA Kits)-dependent molecular mechanisms of glucose homeostasis, and suggests that PEDF could be a specific target in the management of metabolic disorders.

  9. Alpha-2-Antiplasmin (show Alpha2 Antiplasmin ELISA Kits) mediated myofibroblast formation and the development of renal fibrosis in unilateral ureteral obstruction via induction of TGF-beta (show TGFB1 ELISA Kits).

  10. PEDF inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids in diabetic retinopathy.

serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.

Gene names and symbols associated with SERPINF1

  • serpin family F member 1 (SERPINF1) antibody
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (serpinf1) antibody
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 L homeolog (serpinf1.L) antibody
  • serpin family F member 1 (Serpinf1) antibody
  • serine (or cysteine) peptidase inhibitor, clade F, member 1 (Serpinf1) antibody
  • AI195227 antibody
  • Dmrs91 antibody
  • EPC-1 antibody
  • MGC82984 antibody
  • OI6 antibody
  • OI12 antibody
  • Pedf antibody
  • Pedfl antibody
  • Sdf3 antibody
  • SERPINF1 antibody
  • zgc:92072 antibody

Protein level used designations for SERPINF1

cell proliferation-inducing gene 35 protein , pigment epithelium-derived factor , serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 , serpin F1 , alpha-2 antiplasmin , pigment epithelium derived factor , serpin peptidase inhibitor, clade F, member 1 , serpin-F1 , serine (or cysteine) proteinase inhibitor, clade F), member 1 , serine (or cysteine) proteinase inhibitor, clade F, member 1 , serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 , alpha-2 antiplasmin, pigment epithelium derived factor , pigment epithelium-derived factor-like , SDF-3 , caspin , stromal cell derived factor 3 , stromal cell-derived factor 3 , serine (or cysteine) peptidase inhibitor, clade F, member 1

GENE ID SPECIES
5176 Homo sapiens
780402 Sus scrofa
281386 Bos taurus
394686 Xenopus (Silurana) tropicalis
417561 Gallus gallus
444412 Xenopus laevis
468137 Pan troglodytes
611276 Canis lupus familiaris
100072415 Equus caballus
100192425 Ovis aries
100216362 Cavia porcellus
100403187 Callithrix jacchus
100457889 Pongo abelii
100482247 Ailuropoda melanoleuca
100580793 Nomascus leucogenys
20317 Mus musculus
287526 Rattus norvegicus
447800 Danio rerio
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