AFT7 Products
(Activating Transcription Factor 7 (AFT7))
Categories
Isoform 4/ATF-A0 acts as a dominant repressor of the E- selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation. Plays important functions in early cell signaling. Binds 3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.
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Featured AFT7 Categories
AFT7 Antibodies
High quality antibodies with extensive validation data.
AFT7 ELISA Kits
Reliable ELISA kits for a wide range of species.
AFT7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AFT7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7441865
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (5)
Cat. No.
ABIN6256915
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (4)
Cat. No.
ABIN7148809
Quantity
100 μL
Datasheet
Datasheet
Recommended AFT7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380938
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse
Analytical Method
Qualitative DNA-Binding ELISA
Validations
Cat. No.
ABIN5648457
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN770532
Quantity
96 tests
Datasheet
Datasheet
Recommended AFT7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345950
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345952
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7416553
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our AFT7 products
: "Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase." in: PLoS ONE, Vol. 9, Issue 12, pp. e116048, (2014) (PubMed).: "A functional interaction between ATF7 and TAF12 that is modulated by TAF4." in: Oncogene, Vol. 24, Issue 21, pp. 3472-83, (2005) (PubMed).
: "ATF-7, a novel bZIP protein, interacts with the PRL-1 protein-tyrosine phosphatase." in: The Journal of biological chemistry, Vol. 276, Issue 17, pp. 13718-26, (2001) (PubMed).
Synonyms and alternative names related to AFT7
activating transcription factor 7 (ATF7), activating transcription factor 7 (Atf7), activating transcription factor 7b (atf7b), activating transcription factor 7 (atf7), 1110012F10Rik, 9430065F09Rik, AI549878, ATF7, ATFA, atfa, C130020M04Rik, fa97a09, fc25b12, wu:fa97a09, wu:fc25b12Protein level used designations for AFT7
- cyclic AMP-dependent transcription factor ATF-7
- transcription factor ATF-A
- cAMP-dependent transcription factor ATF-7
- activating transcription factor 7
- cyclic AMP-dependent transcription factor ATF-7-like
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