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AFT7 Products

(Activating Transcription Factor 7 (AFT7))

Categories

Isoform 4/ATF-A0 acts as a dominant repressor of the E- selectin/NF-ELAM1/delta-A promoter. Isoform 5/ATF-4 acts as a negative regulator, inhibiting both ATF2 and ATF7 transcriptional activities. It may exert these effects by sequestrating in the cytoplasm the Thr-53 phosphorylating kinase, preventing activation. Plays important functions in early cell signaling. Binds 3'), a sequence present in many viral and cellular promoters. Activator of the NF-ELAM1/delta-A site of the E-selectin promoter. Has no intrinsic transcriptional activity, but activates transcription on formation of JUN or FOS heterodimers. Also can bind TRE promoter sequences when heterodimerized with members of the JUN family.

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Featured AFT7 Categories

AFT7 Antibodies

High quality antibodies with extensive validation data.

AFT7 ELISA Kits

Reliable ELISA kits for a wide range of species.

AFT7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AFT7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, ICC, IF, WB
Validations
  • (5)
Cat. No. ABIN6256915
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, IF, ELISA, WB
Validations
  • (5)
Cat. No. ABIN3028450
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, WB
Validations
  • (4)
Cat. No. ABIN7148809
Quantity 100 μL
Datasheet Datasheet

Recommended AFT7 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1113261
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380938
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative DNA-Binding ELISA
Validations
Cat. No. ABIN5648457
Quantity 96 tests
Datasheet Datasheet

Recommended AFT7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3126575
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3089360
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345950
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our AFT7 products

Hasegawa, Ishibashi, Kubota, Yamaguchi, Yuki, Nakajo, Eckner, Yamaguchi, Yokoyama, Yamaguchi: "Cdk1-mediated phosphorylation of human ATF7 at Thr-51 and Thr-53 promotes cell-cycle progression into M phase." in: PLoS ONE, Vol. 9, Issue 12, pp. e116048, (2014) (PubMed).

Hamard, Dalbies-Tran, Hauss, Davidson, Kedinger, Chatton: "A functional interaction between ATF7 and TAF12 that is modulated by TAF4." in: Oncogene, Vol. 24, Issue 21, pp. 3472-83, (2005) (PubMed).

Peters, Liang, Li, Kannan, Peng, Taub, Diamond: "ATF-7, a novel bZIP protein, interacts with the PRL-1 protein-tyrosine phosphatase." in: The Journal of biological chemistry, Vol. 276, Issue 17, pp. 13718-26, (2001) (PubMed).

Synonyms and alternative names related to AFT7

activating transcription factor 7 (ATF7), activating transcription factor 7 (Atf7), activating transcription factor 7b (atf7b), activating transcription factor 7 (atf7), 1110012F10Rik, 9430065F09Rik, AI549878, ATF7, ATFA, atfa, C130020M04Rik, fa97a09, fc25b12, wu:fa97a09, wu:fc25b12

Protein level used designations for AFT7

  • cyclic AMP-dependent transcription factor ATF-7
  • transcription factor ATF-A
  • cAMP-dependent transcription factor ATF-7
  • activating transcription factor 7
  • cyclic AMP-dependent transcription factor ATF-7-like
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