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Activin A Receptor Type IB/ALK-4 Products

(Activin A Receptor, Type IB (ACVR1B))

Categories

This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010].

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Featured Activin A Receptor Type IB/ALK-4 Categories

Activin A Receptor Type IB/ALK-4 Antibodies

High quality antibodies with extensive validation data.

Activin A Receptor Type IB/ALK-4 ELISA Kits

Reliable ELISA kits for a wide range of species.

Activin A Receptor Type IB/ALK-4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Activin A Receptor Type IB/ALK-4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7101463
Quantity 20 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (1)
  • (4)
Cat. No. ABIN559768
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS
Validations
  • (4)
Cat. No. ABIN392231
Quantity 400 μL
Datasheet Datasheet

Recommended Activin A Receptor Type IB/ALK-4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648129
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4881724
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730326
Quantity 96 tests
Datasheet Datasheet

Recommended Activin A Receptor Type IB/ALK-4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Human Cells
Validations
  • (1)
Cat. No. ABIN7320467
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7121675
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305803
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Activin A Receptor Type IB/ALK-4 products

Portale, Cricrì, Bresolin, Lupi, Gaspari, Silvestri, Russo, Marino, Ubezio, Pagni, Vergani, Kronnie, Valsecchi, Locatelli, Rizzari, Biondi, Dander, DAmico: "ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells." in: Haematologica, Vol. 104, Issue 3, pp. 533-545, (2019) (PubMed).

Tengroth, Arebro, Larsson, Bachert, Georén, Cardell: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." in: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).

Dong, Liu, Meng, Liu, Bi, Wu, Jin, Yao, Tang, Wang, Li, Zhang, Yu, Zhan, Chen, Ge, Yang, Li: "Keratin 8 limits TLR-triggered inflammatory responses through inhibiting TRAF6 polyubiquitination." in: Scientific reports, Vol. 6, pp. 32710, (2018) (PubMed).

Zhu, Xu, Cuascut, Hall, Oxford: "Activin acutely sensitizes dorsal root ganglion neurons and induces hyperalgesia via PKC-mediated potentiation of transient receptor potential vanilloid I." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 27, Issue 50, pp. 13770-80, (2007) (PubMed).

Mukasa, Nomura, Tanaka, Tanaka, Nishi, Okabe, Goto, Yanase, Nawata: "Activin signaling through type IB activin receptor stimulates aromatase activity in the ovarian granulosa cell-like human granulosa (KGN) cells." in: Endocrinology, Vol. 144, Issue 4, pp. 1603-11, (2003) (PubMed).

Harrison, Gray, Koerber, Fischer, Vale: "Identification of a functional binding site for activin on the type I receptor ALK4." in: The Journal of biological chemistry, Vol. 278, Issue 23, pp. 21129-35, (2003) (PubMed).

Danila, Zhang, Zhou, Haidar, Klibanski: "Overexpression of wild-type activin receptor alk4-1 restores activin antiproliferative effects in human pituitary tumor cells." in: The Journal of clinical endocrinology and metabolism, Vol. 87, Issue 10, pp. 4741-6, (2002) (PubMed).

Synonyms and alternative names related to Activin A Receptor Type IB/ALK-4

activin A receptor type 1B (ACVR1B), activin A receptor type 1B (acvr1b), Activin receptor type-1B (acv1b), activin A receptor, type IB (ACVR1B), activin A receptor, type 1B (Acvr1b), activin A receptor type 1B (Acvr1b), activin A receptor type 1Ba (acvr1ba), 6820432J04, ActR-IB, actrib, ActRIB, ACTRIB, ACVR1B, acvrlk4, Acvrlk4, ACVRLK4, alk-4, alk4, Alk4, ALK4, axis, DKFZp469A1614, skr2, SKR2, Skr2, taram-a, tarama, wu:fb75f01, xalk4

Protein level used designations for Activin A Receptor Type IB/ALK-4

  • activin A receptor, type IB
  • activin A receptor, type 1B
  • activin type IB receptor
  • activin receptor type-1B-like
  • Activin receptor type-1B
  • activin receptor IB
  • ALK-4
  • activin receptor type IB
  • activin receptor type-1B
  • activin receptor-like kinase 4
  • serine/threonine-protein kinase receptor R2
  • activin A receptor, type II-like kinase 4
  • ACTR-IB
  • Serine/threonine-protein kinase receptor R2
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