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AMBRA1 Products

(Autophagy/beclin-1 Regulator 1 (AMBRA1))

Categories

Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation.

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Featured AMBRA1 Categories

AMBRA1 Antibodies

High quality antibodies with extensive validation data.

AMBRA1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AMBRA1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN3021394
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IP
Validations
  • (2)
  • (5)
Cat. No. ABIN347117
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (1)
  • (3)
Cat. No. ABIN704741
Quantity 100 μL
Datasheet Datasheet

Recommended AMBRA1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6210307
Quantity 96 tests
Datasheet Datasheet

Recommended AMBRA1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3088867
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3130745
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2714648
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our AMBRA1 products

Nobili, Krashia, Cordella, La Barbera, DellAcqua, Caruso, Pignataro, Marino, Sciarra, Biamonte, Scattoni, Ammassari-Teule, Cecconi, Berretta, Keller, Mercuri, DAmelio: "Ambra1 Shapes Hippocampal Inhibition/Excitation Balance: Role in Neurodevelopmental Disorders." in: Molecular neurobiology, Vol. 55, Issue 10, pp. 7921-7940, (2018) (PubMed).

Ugun-Klusek, Tatham, Elkharaz, Constantin-Teodosiu, Lawler, Mohamed, Paine, Anderson, John Mayer, Lowe, Ellen Billett, Bedford: "Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway." in: Cell death & disease, Vol. 8, Issue 1, pp. e2531, (2017) (PubMed).

Falasca, Torino, Marconi, Costantini, Pompeo, Sentinelli, De Salvo, Patrizio, Padula, Gallucci, Piacentini, Malorni: "AMBRA1 and SQSTM1 expression pattern in prostate cancer." in: Apoptosis : an international journal on programmed cell death, Vol. 20, Issue 12, pp. 1577-86, (2015) (PubMed).

Song, Kou, Zou, Gao, Zeng, Xie: "Involvement of autophagy in tri-ortho-cresyl phosphate- induced delayed neuropathy in hens." in: Neurochemistry international, Vol. 64, pp. 1-8, (2013) (PubMed).

Armstrong, Corazzari, Martin, Pagliarini, Falasca, Hill, Ellis, Al Sabah, Redfern, Fimia, Piacentini, Lovat: "Oncogenic B-RAF signaling in melanoma impairs the therapeutic advantage of autophagy inhibition." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 17, Issue 8, pp. 2216-26, (2011) (PubMed).

Van Humbeeck, Cornelissen, Hofkens, Mandemakers, Gevaert, De Strooper, Vandenberghe: "Parkin interacts with Ambra1 to induce mitophagy." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10249-61, (2011) (PubMed).

Di Bartolomeo, Corazzari, Nazio, Oliverio, Lisi, Antonioli, Pagliarini, Matteoni, Fuoco, Giunta, DAmelio, Nardacci, Romagnoli, Piacentini, Cecconi, Fimia: "The dynamic interaction of AMBRA1 with the dynein motor complex regulates mammalian autophagy." in: The Journal of cell biology, Vol. 191, Issue 1, pp. 155-68, (2010) (PubMed).

Fimia, Stoykova, Romagnoli, Giunta, Di Bartolomeo, Nardacci, Corazzari, Fuoco, Ucar, Schwartz, Gruss, Piacentini, Chowdhury, Cecconi: "Ambra1 regulates autophagy and development of the nervous system." in: Nature, Vol. 447, Issue 7148, pp. 1121-5, (2007) (PubMed).

Gozuacik, Kimchi: "Autophagy as a cell death and tumor suppressor mechanism." in: Oncogene, Vol. 23, Issue 16, pp. 2891-906, (2004) (PubMed).

Synonyms and alternative names related to AMBRA1

autophagy and beclin 1 regulator 1 (AMBRA1), autophagy/beclin-1 regulator 1a (ambra1a), autophagy/beclin 1 regulator 1 (Ambra1), autophagy and beclin 1 regulator 1 (Ambra1), 2310079H06Rik, A130023A14, AA474864, AV021921, D030051N19Rik, DCAF3, mKIAA1736, Nyw1, WDR94

Protein level used designations for AMBRA1

  • autophagy/beclin-1 regulator 1
  • activating molecule in BECN1-regulated autophagy protein 1-like
  • activating molecule in BECN1-regulated autophagy protein 1
  • activating molecule in Beclin1-regulated autophagy
  • ischemia related factor NYW-1
  • DDB1 and CUL4 associated factor 3
  • WD repeat domain 94
  • activating molecule in beclin-1-regulated autophagy
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