Browse our STRADB Proteins (STRADB)

Full name:: STE20-Related Kinase Adaptor beta Proteins (STRADB)

On www.antibodies-online.com are 5 STE20-Related Kinase Adaptor beta (STRADB) Proteins from 2 different suppliers available. Additionally we are shipping STRADB Antibodies (113) and many more products for this protein. A total of 129 STRADB products are currently listed.

Synonyms:: AA792893, ALS2CR2, B830008M19, CALS-21, D1Ucla2, ILPIP, ILPIPA, MGC82468, PAPK, PRO1038, RGD1559449, STRADB, Syradb

list all proteins	Gene Name	GeneID	UniProt
Rat STRADB	STRADB	501146
	STRADB	227154	Q8K4T3
	STRADB	55437	Q9C0K7
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STRADB Proteins (STRADB) by Origin

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Relevant Pathways for STRADB Proteins

AMPK Signaling

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Mouse (Murine) STE20-Related Kinase Adaptor beta (STRADB) interaction partners

Quantitative PCR revealed significantly reduced LKB1 (show STK11 Proteins), MO25alpha (show CAB39 Proteins), and STRADbeta mRNA in LKB1 (show STK11 Proteins)(-/-) muscle. These findings demonstrate that the LKB1 (show STK11 Proteins)-MO25 (show CAB39 Proteins)-STRAD (show STRADA Proteins) complex is the principal AMPKK in skeletal muscle.

Human STE20-Related Kinase Adaptor beta (STRADB) interaction partners

a novel XIAP (show XIAP Proteins)-interacting protein that acts as a co-factor enhancing XIAP (show XIAP Proteins)-mediated activation of JNK1 (show MAPK8 Proteins) and the caspase (show CASP3 Proteins)-independent protection of XIAP (show XIAP Proteins) against apoptosis

STRADB Protein Profile

Protein Summary

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with STRADB

STE20-related kinase adaptor beta (Stradb)
STE20-related kinase adaptor beta (STRADB)
STE20-related kinase adaptor beta L homeolog (stradb.L)

AA792893 protein
ALS2CR2 protein
B830008M19 protein
CALS-21 protein
D1Ucla2 protein
ILPIP protein
ILPIPA protein
MGC82468 protein
PAPK protein
PRO1038 protein
RGD1559449 protein
STRADB protein
Syradb protein

Protein level used designations for STRADB

polyploidy associated protein kinase PAPK-A , amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2 , STE20-related kinase adaptor beta , STE20-related kinase adapter protein beta , juvenile amyotrophic lateral sclerosis 2 candidate 2 , STE20-related kinase adapter protein beta-like , ILP-interacting protein homolog , STRAD beta , amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein homolog , polyploidy associated protein kinase , polyploidy-associated protein kinase , pseudokinase ALS2CR2 , ILP-interacting protein ILPIPA , amyotrophic lateral sclerosis 2 chromosomal region candidate gene 2 protein

GENE ID	SPECIES
501146	Rattus norvegicus
100225181	Taeniopygia guttata
432123	Xenopus laevis
459878	Pan troglodytes
478870	Canis lupus familiaris
506029	Bos taurus
641449	Macaca mulatta
100013258	Monodelphis domestica
100066574	Equus caballus
100342882	Oryctolagus cuniculus
100396910	Callithrix jacchus
100434354	Pongo abelii
100473351	Ailuropoda melanoleuca
100511661	Sus scrofa
100594976	Nomascus leucogenys
227154	Mus musculus
55437	Homo sapiens

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