VNN2 antibody (PE)

Catalog No. ABIN1109469

Product Details anti-VNN2 Antibody (PE)

Target: VNN2 (Vanin 2 (VNN2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This VNN2 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: This antibody reacts with human GPI-80 on flow cytometry. It does not react with mouse or rat neutrophils.

Purification: Protein A agarose

Immunogen: PMA activated human neutrophil

Clone: 3H9

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 50 tests in 1 mL PBS, 0.09 % NaN3, 1 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2 - 8 °C.

Target Details for VNN2

Target: VNN2 (Vanin 2 (VNN2))

Alternative Name: Vanin-2 / FOAP-4 (VNN2 Products)

Background: The GPI-80 Molecule (80 kDa) recognized by this antibody (clone 3H9) was shown to be present on human neutrophils. When 3H9 was added with a neutrophil stimulant (fMLP), the inhibition of neutrophil adherence was observed after 60 minutes incubation. 3H9 enhanced not only fMLP-induced chemotaxis but random migration of neutrophils as well. Furthermore, 3H9 clearly discriminated neutrophils from both basophils and eosinophils derived from humans.Synonyms: Glycosylphosphatidyl inositol-anchored protein GPI-80, VNN2, Vascular non-inflammatory molecule 2

Gene ID: 8875

NCBI Accession: NP_001229279

UniProt: O95498