KRT8 antibody (Keratin 8)

Catalog No. ABIN112323

Product Details anti-KRT8 Antibody

Target: KRT8

Reactivity: Human, Cow, Pig, Sheep

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT8 antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)

Specificity: The antibody reacts with Cytokeratin 8 (52.5 kDa).

Cross-Reactivity (Details): Species reactivity (tested):Human, Bovine, Porcine, Sheep.

Purification: Protein A affinity chromatography

Purity: > 95 % by SDS-PAGE

Immunogen: Cytoskeleton preparation from HeLa cells

Clone: C-51

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry on frozen and paraffin embedded sections. Immunoprecipitation. Western Blotting. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.4, 15 mM Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for KRT8

Target: KRT8

Alternative Name: Cytokeratin 8 (KRT8 Antibody Abstract)

Synonyms: CARD2, CK-8, CK8, CYK8, K2C8, K8, KO, AA960620, AL022697, AU019895, Card2, EndoA, Krt-2.8, Krt2-8, CYKER, KRT2-8, KERATIN8, ck8, cyk8, k2c8, card2, krt2-5, MGC69490, KRT8, DreK8, cb186, krt2-8, sb:cb186, wu:fa20h05, wu:fa95h10, wu:fb96c06, zf-K8, zfk8, DKFZp468F2127, keratin 8, keratin 8 S homeolog, KRT8, Krt8, krt8.S, krt8

Background: Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8

Gene ID: 3856

NCBI Accession: NP_002264

UniProt: P05787