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KRT8 antibody (AA 391-483)

KRT8 Reactivity: Human WB, IHC, ELISA, ICC Host: Mouse Monoclonal 8A5D12 unconjugated
Catalog No. ABIN969080
  • Target See all KRT8 Antibodies
    KRT8 (Keratin 8 (KRT8))
    Binding Specificity
    • 18
    • 16
    • 13
    • 12
    • 10
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 391-483
    Reactivity
    • 247
    • 81
    • 76
    • 32
    • 32
    • 30
    • 30
    • 16
    • 14
    • 10
    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 132
    • 124
    • 2
    • 1
    Mouse
    Clonality
    • 129
    • 128
    Monoclonal
    Conjugate
    • 137
    • 23
    • 17
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    This KRT8 antibody is un-conjugated
    Application
    • 163
    • 97
    • 88
    • 83
    • 66
    • 50
    • 41
    • 40
    • 31
    • 29
    • 23
    • 18
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Purification
    purified
    Immunogen
    Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. coli.
    Clone
    8A5D12
    Isotype
    IgG1
    Top Product
    Discover our top product KRT8 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Walker, Harris, Holloway, McKenzie, Wells, Robinson, Morris: "Cytokeratin KRT8/18 expression differentiates distinct subtypes of grade 3 invasive ductal carcinoma of the breast." in: Cancer genetics and cytogenetics, Vol. 178, Issue 2, pp. 94-103, (2007) (PubMed).

  • Target
    KRT8 (Keratin 8 (KRT8))
    Alternative Name
    Cytokeratin 8 (KRT8 Products)
    Synonyms
    CARD2 antibody, CK-8 antibody, CK8 antibody, CYK8 antibody, K2C8 antibody, K8 antibody, KO antibody, AA960620 antibody, AL022697 antibody, AU019895 antibody, Card2 antibody, EndoA antibody, Krt-2.8 antibody, Krt2-8 antibody, CYKER antibody, KRT2-8 antibody, KERATIN8 antibody, ck8 antibody, cyk8 antibody, k2c8 antibody, card2 antibody, krt2-5 antibody, MGC69490 antibody, KRT8 antibody, DreK8 antibody, cb186 antibody, krt2-8 antibody, sb:cb186 antibody, wu:fa20h05 antibody, wu:fa95h10 antibody, wu:fb96c06 antibody, zf-K8 antibody, zfk8 antibody, DKFZp468F2127 antibody, keratin 8 antibody, keratin 8 S homeolog antibody, KRT8 antibody, Krt8 antibody, krt8.S antibody, krt8 antibody
    Background

    Description: Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.

    Aliases: CK8, CYK8, K2C8, KRT8

    Molecular Weight
    54 kDa
    Gene ID
    3856
    HGNC
    3856
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