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5HT1D antibody (Serotonin Receptor 1D) (AA 2-110) (Alexa Fluor 488) Primary Antibody

HTR1D Reactivity: Mouse IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN1394842
$442.20
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target
    5HT1D (HTR1D)
    Binding Specificity
    • 14
    • 9
    • 9
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-110
    Reactivity
    • 45
    • 24
    • 15
    • 1
    • 1
    Mouse
    Host
    • 52
    Rabbit
    Clonality
    • 52
    Polyclonal
    Conjugate
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This 5HT1D antibody is conjugated to Alexa Fluor 488
    Application
    • 28
    • 22
    • 12
    • 12
    • 11
    • 6
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Rabbit, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human 5HT1D Receptor/SR-1D
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4 °C
    Expiry Date
    12 months
  • Target
    5HT1D (HTR1D)
    Alternative Name
    5HT1D Receptor/SR-1D (HTR1D Antibody Abstract)
    Synonyms
    AI853647, Gpcr14, Htr1db, 5-HT1D, HT1DA, HTR1DA, HTRL, RDC4, 5HT1D, 5-HT-1D, 5-hydroxytryptamine (serotonin) receptor 1D, 5-hydroxytryptamine receptor 1D, Htr1d, HTR1D
    Background

    The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-17 (5HT17). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

    Subcellular location: Cell membrane

    Synonyms: 5-hydroxytryptamine receptor 1D, 5-HT-1D, 5-HT1D, Serotonin 1D alpha receptor, 5-HT-1D-alpha, Serotonin receptor 1D

    Gene ID
    3352
    UniProt
    P28221
    Pathways
    JAK-STAT Signaling
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