5HT1D antibody (AA 150-250)

Catalog No. ABIN7270237

This Rabbit Polyclonal antibody specifically detects 5HT1D in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for 5HT1D antibody (AA 150-250) (ABIN7270237)

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This 5HT1D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-5HT1D Antibody

Binding Specificity: AA 150-250

Purpose: HTR1D Rabbit pAb

Sequence: RTAGHAATMI AIVWAISICI SIPPLFWRQA KAQEEMSDCL VNTSQISYTI YSTCGAFYIP SVLLIILYGR IYRAARNRIL NPPSLYGKRF TTAHLITGSA G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HTR1D (NP_000855.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for 5HT1D

Target: 5HT1D (HTR1D) (Serotonin Receptor 1D (HTR1D))

Alternative Name: HTR1D

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin. Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction.,HTR1D,5-HT1D,HT1DA,HTR1DA,HTRL,RDC4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Neuroscience,HTR1D

Molecular Weight: 41kDa

Gene ID: 3352

UniProt: P28221

Pathways: JAK-STAT Signaling