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HTR7 antibody (5-Hydroxytryptamine (serotonin) Receptor 7 (Adenylate Cyclase-Coupled)) (AA 51-150) (Alexa Fluor 647) Primary Antibody

HTR7 Reactivity: Mouse, Rat IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN1394904
$442.20
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target
    HTR7
    Binding Specificity
    • 28
    • 14
    • 9
    • 8
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 63
    • 33
    • 31
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 71
    • 7
    Rabbit
    Clonality
    • 78
    Polyclonal
    Conjugate
    • 37
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HTR7 antibody is conjugated to Alexa Fluor 647
    Application
    • 39
    • 38
    • 16
    • 12
    • 12
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human 5HT7 Receptor/SR-7
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store at 4 °C
    Expiry Date
    12 months
  • Target
    HTR7
    Alternative Name
    5HT7 Receptor/SR-7 (HTR7 Antibody Abstract)
    Synonyms
    5-HT7, 5-HT-dro, 5-HT-dro1, 5-HT7Dro, 5-HT[7]Dro, 5-HT[[7Dro]], 5-HT[[7]], 5-HT[[7]]Dro, 5-HT[[dro1]], 5-HTdro1, 5HT-7, 5HT-R1, 5HT-dro, 5HT-dro1, 5HT[[7Dro]], 5htdror, CG12073, DRO1, Dm5HTdro1, Dmel\\CG12073, 5Ht7, 5HT7, htr7-A, 5-hydroxytryptamine receptor 7, 5-hydroxytryptamine (serotonin) receptor 7, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled, 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled L homeolog, HTR7, 5-HT7, LOC752003, Htr7, htr7.L
    Background

    Serotonin (also designated 5-hydroxytryptamine or 5-HT) is a molecule that functions as a neurotransmitter, a hormone and a mitogen, and it is predominantly expressed in the gut, platelets and central nervous system (CNS). In the CNS, serotonin modulates several processes, including anxiety, sleep, appetite, behavior and drug abuse. In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates its effects through several of G protein coupled receptors, designated 5-HT receptors or alternatively SR receptors. SR-3 is a ligand-gated ion channel, whereas all other known serotonin receptor subtypes are G protein-coupled receptors. SR-4 mediates widespread effects in central and peripheral nervous systems. SR-7 belongs to the superfamily of G protein-coupled receptors. The gene which encodes SR-7 maps to human chromosome 10q21-q24.

    Subcellular location: Cell membrane

    Synonyms: HT 7, 5 HT X, 5 hydroxytryptamine serotonin receptor 7 adenylate cyclase coupled, 5 hydroxytryptamine serotonin receptor 7, 5 hydroxytryptamine receptor 7, 5-HT-7, 5-HT-X, 5-HT7, 5-hydroxytryptamine receptor 7, 5HT7, 5HT7R_HUMAN, HTR7, Serotonin 5 HT 7 receptor, Serotonin receptor 7.

    Gene ID
    3363
    UniProt
    P34969
    Pathways
    JAK-STAT Signaling
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