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CARTPT antibody (CART Prepropeptide) AA 31-116 (Biotin) Primary Antibody

CARTPT Reactivity: Human IHC (fro), IHC (p) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1395427
$453.20
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all CARTPT Antibodies
    CARTPT
    Binding Specificity
    • 14
    • 9
    • 9
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 31-116
    Reactivity
    • 37
    • 33
    • 19
    • 2
    Human
    Host
    • 52
    • 4
    • 1
    Rabbit
    Clonality
    • 53
    • 4
    Polyclonal
    Conjugate
    • 24
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CARTPT antibody is conjugated to Biotin
    Application
    • 32
    • 29
    • 22
    • 13
    • 13
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CART
    Isotype
    IgG
  • Application Notes
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Target
    CARTPT
    Alternative Name
    CART (CARTPT Products)
    Synonyms
    CART, Cart, CARTPT, CART prepropeptide, CARTPT, Cartpt
    Background

    The CART gene encodes for a protein which has an important role in the regulation of appetite and body weight. The CART (cocaine- and amphetamine-regulated transcript) neuropeptide is an mRNA that changes in response to psychostimulant drug administration. Injection of CART peptides into the ventral tegmental area produces psychostimulant-like effects. CART localizes to areas of the central and peripheral nervous systems and is involved in feeding behavior when injected centrally. Expression of CART in the rat hypothalamus is modulated by nutritional status, and injection of synthetic CART peptide into the forebrain ventricular system suppresses food intake, indicating a possible role in hypothalamic control of energy homeostasis. Its identification in cell bodies and central terminals of vagal afferent neurons additionally suggests a role in brainstem mechanisms of meal termination and satiety.

    Subcellular location: Secreted

    Synonyms: CART, CART prepropeptide, Cocaine and amphetamine regulated transcript, CART_HUMAN.

    Pathways
    Hormone Transport, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Feeding Behaviour
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