Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PEN2 antibody (Presenilin Enhancer 2 Homolog) AA 6-80 (Biotin) Primary Antibody

PSENEN Reactivity: Mouse, Rat IHC (fro), IHC (p), WB Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1397397
$453.20
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all PEN2 (PSENEN) Antibodies
    PEN2 (PSENEN)
    Binding Specificity
    • 14
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 6-80
    Reactivity
    • 35
    • 32
    • 27
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 37
    • 4
    Rabbit
    Clonality
    • 30
    • 11
    Polyclonal
    Conjugate
    • 21
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PEN2 antibody is conjugated to Biotin
    Application
    • 23
    • 14
    • 14
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Specificity
    Belongs to the PEN-2 family
    Predicted Reactivity
    Human,Dog,Cow,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PEN2
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C
    Expiry Date
    12 months
  • Target
    PEN2 (PSENEN)
    Alternative Name
    PEN2 (PSENEN Products)
    Synonyms
    MSTP064, PEN-2, PEN2, Psenen, ACYPI006208, 1700023M09Rik, Pen-2, RGD1312037, CG33198, Dmel\\CG33198, anon-AE003800.1, dPen-2, psenen, pen-2, pen2, zgc:109727, presenilin enhancer gamma-secretase subunit, presenilin enhancer 2, presenilin enhancer gamma secretase subunit, Gamma-secretase subunit pen-2, presenilin enhancer, presenilin enhancer gamma secretase subunit S homeolog, PSENEN, PEN2, Psenen, pen-2, psenen.S, psenen
    Background

    Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: PEN2, PEN-2, MDS033, MSTP064, Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN

    Gene ID
    UniProt
    Q9NZ42
    Pathways
    Notch Signaling, Neurotrophin Signaling Pathway
You are here:
help Support