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TRPM5 antibody (Transient Receptor Potential Cation Channel, Subfamily M, Member 5) (Alexa Fluor 350) Primary Antibody

TRPM5 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1400529
$476.30
Plus shipping costs $45.00
100 μL
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  • Target See all TRPM5 Antibodies
    TRPM5
    Reactivity
    • 35
    • 26
    • 23
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 33
    • 6
    Rabbit
    Clonality
    • 39
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRPM5 antibody is conjugated to Alexa Fluor 350
    Application
    • 28
    • 13
    • 12
    • 11
    • 6
    • 3
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TRPM5
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    TRPM5
    Alternative Name
    TRPM5 (TRPM5 Products)
    Synonyms
    LTRPC5, MTR1, 9430099A16Rik, LTrpC-5, Ltrpc5, Mtr1, transient receptor potential cation channel subfamily M member 5, transient receptor potential cation channel, subfamily M, member 5, TRPM5, Trpm5, trpm5
    Background

    Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). Also activated by a fast intracellular Ca(2+) increase in response to inositol 1,4,5-triphosphate-producing receptor agonists. The channel is blocked by extracellular acidification. External acidification has 2 effects, a fast reversible block of the current and a slower irreversible enhancement of current inactivation. Is a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. Heat activation is due to a shift of the voltage-dependent activation curve to negative potentials. Activated by arachidonic acid in vitro. May be involved in perception of bitter, sweet and umami tastes. May also be involved in sensing semiochemicals.

    Subcellular location: Extracellular

    Synonyms: MLSN1 and TRP related gene 1, MLSN1 and TRP related gene 1 protein, MLSN1 and TRP-related, MLSN1- and TRP-related gene 1 protein, MTR1, Novel protein similar to vertebrate transient receptor potential cation channel, subfamily M, member 5 , Transient receptor potential cation channel subfamily M member 5, Transient receptor potential cation channel, subfamily M, member 5, Trpm5, TRPM5 transient receptor potential cation channel, subfamily M, member 5, TRPM5_HUMAN, 9430099A16Rik, Long transient receptor potential channel 5, LTrpC-5, LTrpC5.

    Gene ID
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