TRPM5 antibody (N-Term)

Catalog No. ABIN2776205

This Rabbit Polyclonal antibody specifically detects TRPM5 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Cow, Dog and Horse.

Quick Overview for TRPM5 antibody (N-Term) (ABIN2776205)

Target: TRPM5 (Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5))

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPM5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TRPM5 Antibody

Binding Specificity: N-Term

Sequence: EKHISEQRAG YGGTGSIEIP VLCLLVNGDP NTLERISRAV EQAAPWLILV

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TRPM5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRPM5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1165 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRPM5

Target: TRPM5 (Transient Receptor Potential Cation Channel, Subfamily M, Member 5 (TRPM5))

Alternative Name: TRPM5

Background: TRPM5 is a voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. It is activated by arachidonic acid in vitro. It may be involved in perception of bitter, sweet and umami tastes. It may also be involved in sensing semiochemicals.
Alias Symbols: LTRPC5, MTR1
Protein Size: 1165

Molecular Weight: 131 kDa

Gene ID: 29850

NCBI Accession: NM_014555, NP_055370

UniProt: Q9NZQ8