PTPN1 antibody (pSer50)

Catalog No. ABIN1531514

Product Details anti-PTPN1 Antibody

Target: PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))

Binding Specificity: AA 16-65, pSer50

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTPN1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Western Blotting (WB)

Specificity:

PTP1B (Phospho-Ser50) Antibody detects endogenous levels of PTP1B only when phosphorylated at Ser50.

PhosphorylationH:S50 M:S50 R:S50

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human PTP1B around the phosphorylation site of Ser50.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000

Comment:

Unigene-Number: Hs.417549 (NCBI Gene Symbol: PTPN1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for PTPN1

Target: PTPN1 (Protein tyrosine Phosphatase, Non-Receptor Type 1 (PTPN1))

Alternative Name: PTP1B (PTPN1 Products)

Synonyms: PTPN1 antibody, PTP1B antibody, PTP-1B antibody, PTP-HA2 antibody, Ptp antibody, ptp1b antibody, wu:fk54h03 antibody, CPTP1 antibody, protein tyrosine phosphatase, non-receptor type 1 antibody, protein tyrosine phosphatase, non-receptor type 1 L homeolog antibody, PTPN1 antibody, Ptpn1 antibody, ptpn1 antibody, ptpn1.L antibody

Background:

Synonyms: CPTP1, Protein-protein-tyrosine phosphatase HA2, Protein-tyrosine phosphatase 1B, Protein-tyrosine phosphatase, non-receptor type 1, PTN1, PTP-1B, PTP-HA2, PTPN1

NCBI Gene Symbol: PTPN1

Molecular Weight: 49 kDa

Gene ID: 5770

OMIM: 176885

UniProt: P18031

Pathways: TLR Signaling, Response to Growth Hormone Stimulus, ER-Nucleus Signaling, Platelet-derived growth Factor Receptor Signaling