Aconitase 1 antibody (pSer138)

Catalog No. ABIN1531675

Product Details anti-Aconitase 1 Antibody

Target: Aconitase 1 (ACO1)

Binding Specificity: AA 106-155, pSer138

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aconitase 1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Specificity:

IREB1 (Phospho-Ser138) Antibody detects endogenous levels of IREB1 only when phosphorylated at Ser138.

PhosphorylationH:S138 M:S138 R:S138

Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human IREB1 around the phosphorylation site of Ser138.

Isotype: IgG

Application Details

Application Notes: IHC: 1:50~1:100 ELISA: 1:1000

Comment:

Unigene-Number: Hs.567229 (NCBI Gene Symbol: IREB1)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Expiry Date: 12 months

Target Details for Aconitase 1

Target: Aconitase 1 (ACO1)

Alternative Name: IREB1 (ACO1 Products)

Background:

Synonyms: ACO1, aconitase, Aconitate hydratase, citrate hydro-lyase, Ferritin repressor protein, IRE-BP 1, IRE1, IREBP1, iron regulatory protein 1, iron-responsive element binding protein 1, IRP1

NCBI Gene Symbol: IREB1

Molecular Weight: 98 kDa

Gene ID: 48

OMIM: 100880

UniProt: P21399

Pathways: Transition Metal Ion Homeostasis