Aconitase 1 Products
(Aconitase 1 (ACO1))
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Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. [provided by RefSeq, Jul 2008].
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Aconitase 1 Antibodies
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Aconitase 1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Aconitase 1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Aconitase 1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (9)
Cat. No.
ABIN7438541
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7445504
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Application
WB, IHC
Validations
- (8)
Cat. No.
ABIN2778793
Quantity
100 μL
Datasheet
Datasheet
Recommended Aconitase 1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
Cat. No.
ABIN6720599
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953399
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1120137
Quantity
96 tests
Datasheet
Datasheet
Recommended Aconitase 1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305650
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305652
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7279292
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Aconitase 1 products
: "Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth." in: Oncotarget, Vol. 8, Issue 47, pp. 82231-82243, (2017) (PubMed).: "Transferrin receptor mRNA interactions contributing to iron homeostasis." in: RNA (New York, N.Y.), Vol. 22, Issue 8, pp. 1271-82, (2016) (PubMed).
: "Biogenesis of mitochondria in cauliflower (Brassica oleracea var. botrytis) curds subjected to temperature stress and recovery involves regulation of the complexome, respiratory chain activity, ..." in: Biochimica et biophysica acta, Vol. 1847, Issue 4-5, pp. 399-417, (2015) (PubMed).
: "High fat diet subverts hepatocellular iron uptake determining dysmetabolic iron overload." in: PLoS ONE, Vol. 10, Issue 2, pp. e0116855, (2015) (PubMed).
: "Dysregulation of IRP1-mediated iron metabolism causes gamma ray-specific radioresistance in leukemia cells." in: PLoS ONE, Vol. 7, Issue 11, pp. e48841, (2012) (PubMed).
: "IF/TA-related metabolic changes--proteome analysis of rat renal allografts." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 25, Issue 8, pp. 2492-501, (2010) (PubMed).
: "Excess capacity of the iron regulatory protein system." in: The Journal of biological chemistry, Vol. 282, Issue 34, pp. 24650-9, (2007) (PubMed).
Synonyms and alternative names related to Aconitase 1
aconitase 1 (ACO1), aconitase 1 (Aco1), aconitase 1, soluble (ACO1), aconitase 1 L homeolog (aco1.L), Aco-1, Aco1, Acon1, ACONS, AI256519, IREB1, IREBP, Irebp, IREBP1, IRP1, Irp1, Ratireb, ratirebProtein level used designations for Aconitase 1
- IRE-BP 1
- aconitate hydratase, cytoplasmic
- citrate hydro-lyase
- cytoplasmic aconitate hydratase
- ferritin repressor protein
- iron regulatory protein 1
- iron-responsive element binding protein 1
- iron-responsive element-binding protein 1
- IRP1
- IRE-binding protein 1
- Iron responsive element binding protein
- aconitase
- cytoplasmic aconitase
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