EGFR antibody (Epidermal Growth Factor Receptor) (pTyr1172)

Details for Product anti-EGFR Antibody No. ABIN1576203
Target
Binding Specificity
pTyr1172
48
45
39
36
33
32
30
28
26
26
26
25
24
24
23
22
21
20
17
17
16
16
15
15
15
15
15
14
14
13
13
9
9
9
8
6
6
6
6
6
5
5
5
5
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse, Rat
1157
497
465
21
21
13
12
11
11
4
4
3
2
2
2
2
2
1
1
1
1
1
Host
Rabbit
814
300
18
13
13
5
2
1
1
1
Clonality
Polyclonal
Conjugate
This EGFR antibody is un-conjugated
85
44
40
39
28
28
28
28
28
25
21
17
16
16
16
16
16
5
5
5
5
5
5
5
5
5
5
5
5
5
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
ELISA, Western Blotting (WB)
682
346
271
214
209
168
153
150
50
47
41
34
26
22
17
17
12
8
5
4
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Options
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human EGFR around the phosphorylation site of tyrosine 1172 (P-D-YP-Q-Q).
Specificity Epitopes for Species: H:Y1172,M:Y1172,R:Y1171
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatogramphy using non-phosphopeptide corresponding to the phosphorylation site.
Target
Alternative Name EGFR (EGFR Antibody Abstract)
Background ERBB1, Epidermal growth factor receptor precursor, Receptor protein-tyrosine kinase ErbB-1, kinase EGFR
UniProt P00533
Pathways NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Storage -20 °C
Storage Comment Store at -20°C / 1 year
Expiry Date 12 months
Images
Image no. 1 for anti-Epidermal Growth Factor Receptor (EGFR) (pTyr1172) antibody (ABIN1576203) Western blot analysis of extracts from A431 cells untreated or treated with EGF (40μM...