FKBP5 antibody (AA 308-457)

Catalog No. ABIN1679852

Product Details anti-FKBP5 Antibody

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Binding Specificity: AA 308-457

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ESKASESFLL AAFLNLAMCY LKLREYTKAV ECCDKALGLD SANEKGLYRR GEAQLLMNEF ESAKGDFEKV LEVNPQNKAA RLQISMCQKK AKEHNERDRR IYANMFKKFA EQDAKEEANK AMGKKTSEGV TNEKGTDSQA MEEEKPEGHV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 308-457 of human FKBP51/FKBP51/FKBP51/FKBP5 (NP_001139247.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FKBP5

Target: FKBP5 (FK506 Binding Protein 5 (FKBP5))

Alternative Name: FKBP5 (FKBP5 Products)

Background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.,FKBP5,AIG6,FKBP51,FKBP54,P54,PPIase,Ptg-10,Epigenetics & Nuclear Signaling,Signal Transduction,Immunology & Inflammation,FKBP5

Molecular Weight: 30 kDa/51 kDa

Gene ID: 2289

UniProt: Q13451