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MYCBPAP antibody (AA 401-500) (Alexa Fluor 350)

MYCBPAP Reactivity: Mouse, Rat IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1693098
$470.46
Plus shipping costs $45.00
100 μL
Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all MYCBPAP Antibodies
    MYCBPAP (MYCBP Associated Protein (MYCBPAP))
    Binding Specificity
    • 14
    • 1
    • 1
    AA 401-500
    Reactivity
    • 16
    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYCBPAP antibody is conjugated to Alexa Fluor 350
    Application
    • 12
    • 12
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MYCBPAP
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    MYCBPAP (MYCBP Associated Protein (MYCBPAP))
    Alternative Name
    MYCBPAP (MYCBPAP Products)
    Synonyms
    AMAP-1 antibody, AMAP1 antibody, 4932408B01Rik antibody, AW125474 antibody, COD106 antibody, MYCBP associated protein antibody, Mycbp associated protein antibody, MYCBPAP antibody, Mycbpap antibody
    Background

    AMAP-1 (AMY-1-binding protein 1), also known as AMAM-1 or MYCBPAP (MYCBP associated protein), is a 947 amino acid protein that is expressed specifically in testis and is involved in spermatogenesis and synaptic processes. AMAP-1 colocalizes with MYCBP (AMY-1) in cytoplasm and also localizes to membrane. The gene encoding AMAP-1 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: AMAM-1, AMAP-1, AMAP1, AMY-1-binding protein 1, DKFZp434N1415, MYBPP_HUMAN, MYCBP-associated protein, Mycbpap.

    Pathways
    Sensory Perception of Sound
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