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FHOD1 antibody (Formin Homology 2 Domain Containing 1) (pThr1141) (Alexa Fluor 647) Primary Antibody

FHOD1 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN1698648
$442.20
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target
    FHOD1
    Binding Specificity
    pThr1141
    • 14
    • 9
    • 8
    • 8
    • 2
    • 1
    • 1
    Reactivity
    Human, Mouse, Rat
    Host
    Rabbit
    • 35
    • 3
    Clonality
    Polyclonal
    • 37
    • 1
    Conjugate
    This FHOD1 antibody is conjugated to Alexa Fluor 647
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    • 26
    • 16
    • 13
    • 6
    • 2
    • 2
    • 1
    • 1
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human FHOD1 around the phosphorylation site of Thr1141
    Isotype
    IgG
  • Application Notes
    IF(IHC-P): 1:50-200
    Optimal working dilution should be determined by the investigator.
    Comment

    Exitation/Emission: 652nm/668nm

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at 4 °C
    Expiry Date
    12 months
  • Target
    FHOD1
    Alternative Name
    Fhod1 (FHOD1 Antibody Abstract)
    Synonyms
    FHOS, BC017144, FHOS1, formin homology 2 domain containing 1, FHOD1, Fhod1
    Background

    The limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of protein products known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing actin filament assembly. The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. FHOD1 induces the formation of and associates with bundled actin stress fibers in response to the activity of the Rho-ROCK cascade. It influences several cellular activities including cell migration, cytoskeletal arrangement, signal transduction and gene expression.


    Synonyms: FHOD1 phospho T1141, p-FHOD1 phospho T1141, FH1/FH2 domain containing protein, FH1/FH2 domain-containing protein 1, Fhod1, FHOD1_HUMAN, FHOS, FHOS1, Formin homolog overexpressed in spleen 1, Formin homology 2 domain containing 1, Formin homology 2 domain containing protein 1, Formin homology 2 domain-containing protein 1.
    Gene ID
    29109
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