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GMEB1 antibody (Glucocorticoid Modulatory Element Binding Protein 1) (AA 301-400) (Biotin) Primary Antibody

GMEB1 Reactivity: Human ELISA, IHC (fro), IHC (p), WB Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1700878
$419.10
Plus shipping costs $45.00
100 μL
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Delivery in 11 to 16 Business Days
  • Target
    GMEB1
    Binding Specificity
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 301-400
    Reactivity
    • 26
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 22
    • 4
    Rabbit
    Clonality
    • 23
    • 3
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GMEB1 antibody is conjugated to Biotin
    Application
    • 13
    • 13
    • 10
    • 10
    • 6
    • 4
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Cross-Reactivity
    Cow, Horse, Human, Mouse, Rabbit, Rat, Sheep
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human GMEB1
    Isotype
    IgG
  • Application Notes
    WB 1:300-1000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C
    Expiry Date
    12 months
  • Target
    GMEB1
    Alternative Name
    GMEB1 (GMEB1 Antibody Abstract)
    Synonyms
    MGC81052, GMEB1, si:ch211-245h7.5, pif96, p96pif, MGC147529, P96PIF, PIF96, 1110050A04Rik, AI256615, AI481278, RGD1563208, glucocorticoid modulatory element binding protein 1 S homeolog, glucocorticoid modulatory element binding protein 1, gmeb1.S, GMEB1, gmeb1, Gmeb1
    Background

    GMEB-1 is a 573 amino acid protein that contains one SAND domain and is a member of the KDWK family of combinatorial transcription modulators. Localized to both the cytoplasm and the nucleus, GMEB-1 forms a heterodimer with GMEB-2 (Glucocorticoid modulatory element-binding protein 2) and, once associated with GMEB-2, plays a key role in parvovirus DNA replication. In addition, GMEB-1 functions alone as a trans-acting factor that, by binding to glucocorticoid modulatory elements (GMEs) in TAT (tyrosine aminotransferase) promoters, increases intracellular sensitivity to glucocorticoid concentrations. GMEB-1 also interacts with initiator procaspases and, via this interaction, can inhibit caspase-induced apoptosis. Due to alternative splicing events, GMEB-1 is expressed as two isoforms.

    Subcellular location: Cytoplasm, Nucleus

    Synonyms: DNA binding protein p96P, DNA-binding protein p96P, Glucocorticoid modulatory element binding protein 1, Glucocorticoid modulatory element-binding protein 1, GMEB 1, GMEB-1, Gmeb1, GMEB1_HUMAN, P96P, Parvovirus initiation factor p96, P 96, P p96, P96.

    Gene ID
    10691
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