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EMR2 Products

(Egf-Like Module Containing, Mucin-Like, Hormone Receptor-Like 2 (EMR2))

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This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012].

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Featured EMR2 Categories

EMR2 Antibodies

High quality antibodies with extensive validation data.

EMR2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Recommended EMR2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC (p), ICC
Validations
  • (2)
Cat. No. ABIN5577261
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC
Validations
  • (3)
Cat. No. ABIN5013484
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (1)
Cat. No. ABIN3184475
Quantity 100 μL
Datasheet Datasheet

Recommended EMR2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882707
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385460
Quantity 96 tests
Datasheet Datasheet

Recommended EMR2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7416160
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our EMR2 products

Kwakkenbos, Kop, Stacey, Matmati, Gordon, Lin, Hamann: "The EGF-TM7 family: a postgenomic view." in: Immunogenetics, Vol. 55, Issue 10, pp. 655-66, (2004) (PubMed).

Stacey, Chang, Davies, Kwakkenbos, Sanderson, Hamann, Gordon, Lin: "The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans." in: Blood, Vol. 102, Issue 8, pp. 2916-24, (2003) (PubMed).

Kwakkenbos, Chang, Lin, Pouwels, de Jong, van Lier, Gordon, Hamann: "The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells." in: Journal of leukocyte biology, Vol. 71, Issue 5, pp. 854-62, (2002) (PubMed).

Synonyms and alternative names related to EMR2

adhesion G protein-coupled receptor E2 (ADGRE2), adhesion G protein-coupled receptor E2 (LOC484898), CD312, EMR2

Protein level used designations for EMR2

  • egf-like module containing, mucin-like, hormone receptor-like 2
  • EGF-like module-containing mucin-like hormone receptor-like 2
  • EGF-like module containing, mucin-like, hormone receptor-like sequence 2
  • EGF-like module receptor 2
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