LILRB2 antibody (AA 1-100)
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- Target See all LILRB2 Antibodies
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
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Binding Specificity
- AA 1-100
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LILRB2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human LILRB2
- Isotype
- IgG
- Top Product
- Discover our top product LILRB2 Primary Antibody
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IF(IHC-P) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- LILRB2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
- Alternative Name
- LILRB2 (LILRB2 Products)
- Synonyms
- CD85D antibody, ILT-4 antibody, ILT4 antibody, LIR-2 antibody, LIR2 antibody, MIR-10 antibody, MIR10 antibody, leukocyte immunoglobulin-like receptor subfamily A member 3 antibody, leukocyte immunoglobulin like receptor B2 antibody, LOC100433990 antibody, LILRB2 antibody
- Background
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Synonyms: CD85D, CD85 antigen-like family member D, CD85d, CD85d antigen, ILT 4, ILT-4, ILT4, Immunoglobulin like transcript 4, Immunoglobulin-like transcript 4, Leukocyte immunoglobulin like receptor 2, Leukocyte immunoglobulin like receptor subfamily B member 2, Leukocyte immunoglobulin-like receptor 2, Leukocyte immunoglobulin-like receptor subfamily B member 2, Leukocyte immunoglobulin-like receptor, subfamily B with TM and ITIM domains, member 2, LILRA6, LILRB2, LIR 2, LIR-2, LIR2, LIRb, LIRB2_HUMAN, MIR 10, MIR-10, MIR10, Monocyte/macrophage immunoglobulin like receptor 10, Monocyte/macrophage immunoglobulin-like receptor 10.
Background: Leukocyte immunoglobulin-like receptors (LIRs) are members of the immunoglobulin superfamily of glycoproteins and are predominantly expressed by monocytes, B cells, dendritic cells, natural killer (NK) cells, peripheral blood leukocytes and tissues such as placenta, lung and liver. These receptors all contain a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM), have an inhibitory function and are type I membrane proteins. When they bind to MHC (or other ligands) and ITIM is tyrosine phosphorylated, protein-tyrosine phosphatases are recruited and an inhibitory signal cascade triggered. ILT-4, also designated LIR-2, MIR-10 or CD85D antigen, competes with CD8A for binding to class I MHC antigens.
- Gene ID
- 10288
- UniProt
- Q8N423
- Pathways
- Cellular Response to Molecule of Bacterial Origin
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