LILRB2 Products
(Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM and ITIM Domains), Member 2 (LILRB2))
Categories
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured LILRB2 Categories
LILRB2 Antibodies
High quality antibodies with extensive validation data.
LILRB2 ELISA Kits
Reliable ELISA kits for a wide range of species.
LILRB2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended LILRB2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7444112
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (5)
Cat. No.
ABIN5684070
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN564466
Quantity
100 μg
Datasheet
Datasheet
Recommended LILRB2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6968283
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4883446
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6386002
Quantity
96 tests
Datasheet
Datasheet
Recommended LILRB2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (6)
Cat. No.
ABIN7275165
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275187
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (5)
Cat. No.
ABIN7275169
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our LILRB2 products
: "Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells." in: International journal of nanomedicine, Vol. 13, pp. 6941-6960, (2018) (PubMed).: "Human Semaphorin-4A drives Th2 responses by binding to receptor ILT-4." in: Nature communications, Vol. 9, Issue 1, pp. 742, (2018) (PubMed).
: "Co-expression of ILT4/HLA-G in human non-small cell lung cancer correlates with poor prognosis and ILT4-HLA-G interaction activates ERK signaling." in: Tumour biology, Vol. 37, Issue 8, pp. 11187-98, (2017) (PubMed).
: "ILT4 drives B7-H3 expression via PI3K/AKT/mTOR signalling and ILT4/B7-H3 co-expression correlates with poor prognosis in non-small cell lung cancer." in: FEBS letters, Vol. 589, Issue 17, pp. 2248-56, (2015) (PubMed).
: "IFN-γ-rich environment programs dendritic cells toward silencing of cytotoxic immune responses." in: Journal of leukocyte biology, Vol. 95, Issue 1, pp. 33-46, (2014) (PubMed).
: "HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 12, pp. 6184-93, (2012) (PubMed).
: "Immune suppression and resistance mediated by constitutive activation of Wnt/β-catenin signaling in human melanoma cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 5, pp. 2110-7, (2012) (PubMed).
: "Heat shock protein 27 differentiates tolerogenic macrophages that may support human breast cancer progression." in: Cancer research, Vol. 71, Issue 2, pp. 318-27, (2011) (PubMed).
: "Bovine lactoferrin counteracts Toll-like receptor mediated activation signals in antigen presenting cells." in: PLoS ONE, Vol. 6, Issue 7, pp. e22504, (2011) (PubMed).
: "Identification of a new phenotype of tolerogenic human dendritic cells induced by fungal proteases from Aspergillus oryzae." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 7, pp. 3966-76, (2011) (PubMed).
Synonyms and alternative names related to LILRB2
leukocyte immunoglobulin-like receptor subfamily A member 3 (LOC100433990), leukocyte immunoglobulin like receptor B2 (LILRB2), CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10Protein level used designations for LILRB2
- leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
- leukocyte immunoglobulin-like receptor subfamily B member 2-like
- CD85 antigen-like family member D
- Ig-like transcript 4
- leukocyte immunoglobulin-like receptor subfamily B member 2
- monocyte/macrophage immunoglobulin-like receptor 10
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