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TGFBR3 antibody (AA 147-328)

TGFBR3 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 1C5H11 unconjugated
Catalog No. ABIN1724751
  • Target See all TGFBR3 Antibodies
    TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
    Binding Specificity
    • 15
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-328
    Reactivity
    • 54
    • 20
    • 11
    • 2
    Human
    Host
    • 40
    • 12
    • 4
    • 2
    Mouse
    Clonality
    • 45
    • 13
    Monoclonal
    Conjugate
    • 30
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TGFBR3 antibody is un-conjugated
    Application
    • 34
    • 21
    • 13
    • 13
    • 12
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    ELISA, Flow Cytometry (FACS)
    Purpose
    TGFBR3 Antibody
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. Coli.
    Clone
    1C5H11
    Isotype
    IgG2b
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Lambert, Huang, Mythreye, Blobe: "The type III transforming growth factor-? receptor inhibits proliferation, migration, and adhesion in human myeloma cells." in: Molecular biology of the cell, Vol. 22, Issue 9, pp. 1463-72, (2011) (PubMed).

    Jiang, Liu, Lei, You, Zhou, Zhang: "[Defective expression of TGFBR3 gene and its molecular mechanisms in non-small cell lung cancer cell lines]." in: Zhongguo fei ai za zhi = Chinese journal of lung cancer, Vol. 13, Issue 5, pp. 451-7, (2010) (PubMed).

  • Target
    TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
    Alternative Name
    TGFBR3 (TGFBR3 Products)
    Background

    Description: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.


    Aliases: BGCAN, betaglycan

    Molecular Weight
    93.4kDa
    Gene ID
    7049
    HGNC
    7049
    UniProt
    Q03167
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