TGFBR3 antibody (AA 147-328)
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- Target See all TGFBR3 Antibodies
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
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Binding Specificity
- AA 147-328
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TGFBR3 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- TGFBR3 Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. Coli.
- Clone
- 1C5H11
- Isotype
- IgG2b
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The type III transforming growth factor-? receptor inhibits proliferation, migration, and adhesion in human myeloma cells." in: Molecular biology of the cell, Vol. 22, Issue 9, pp. 1463-72, (2011) (PubMed).
: "[Defective expression of TGFBR3 gene and its molecular mechanisms in non-small cell lung cancer cell lines]." in: Zhongguo fei ai za zhi = Chinese journal of lung cancer, Vol. 13, Issue 5, pp. 451-7, (2010) (PubMed).
: "
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The type III transforming growth factor-? receptor inhibits proliferation, migration, and adhesion in human myeloma cells." in: Molecular biology of the cell, Vol. 22, Issue 9, pp. 1463-72, (2011) (PubMed).
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- Target
- TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))
- Alternative Name
- TGFBR3 (TGFBR3 Products)
- Background
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Description: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Aliases: BGCAN, betaglycan
- Molecular Weight
- 93.4kDa
- Gene ID
- 7049
- HGNC
- 7049
- UniProt
- Q03167
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