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DARPP32 antibody (AA 95-204)

PPP1R1B Reactivity: Human ELISA Host: Mouse Monoclonal 2A4G9 unconjugated
Catalog No. ABIN1724915
  • Target See all DARPP32 (PPP1R1B) Antibodies
    DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))
    Binding Specificity
    • 33
    • 18
    • 15
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 95-204
    Reactivity
    • 92
    • 81
    • 74
    • 11
    • 10
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 107
    • 12
    • 1
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 104
    • 19
    Monoclonal
    Conjugate
    • 72
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This DARPP32 antibody is un-conjugated
    Application
    • 92
    • 43
    • 36
    • 27
    • 27
    • 16
    • 15
    • 8
    • 4
    • 3
    • 1
    • 1
    ELISA
    Purpose
    PPP1R1B Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human PPP1R1B (AA: 95-204) expressed in E. Coli.
    Clone
    2A4G9
    Isotype
    IgG1
    Top Product
    Discover our top product PPP1R1B Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Kunii, Ikemoto, Wada, Yang, Kusakabe, Suzuki, Niwa: "Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study." in: Medical molecular morphology, Vol. 44, Issue 4, pp. 190-9, (2011) (PubMed).

    Hamel, Bouchard, Ferrario, Hassan, Aguilar-Mahecha, Buchanan, Quenneville, Miller, Basik: "Both t-Darpp and DARPP-32 can cause resistance to trastuzumab in breast cancer cells and are frequently expressed in primary breast cancers." in: Breast cancer research and treatment, Vol. 120, Issue 1, pp. 47-57, (2010) (PubMed).

  • Target
    DARPP32 (PPP1R1B) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B))
    Alternative Name
    PPP1R1B (PPP1R1B Products)
    Background

    Description: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene.

    Aliases: DARPP32, DARPP-32

    Molecular Weight
    23kDa
    Gene ID
    84152
    HGNC
    84152
    UniProt
    Q9UD71
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