Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) (AA 95-204) antibody

Details for Product No. ABIN1724915
Antigen
  • darpp32
  • darpp-32
  • Darpp-32
  • Darpp32
  • DARPP-32
  • DARPP32
  • AU040756
  • protein phosphatase 1 regulatory inhibitor subunit 1B
  • protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • protein phosphatase 1 regulatory inhibitor subunit 1B S homeolog
  • ppp1r1b
  • PPP1R1B
  • Ppp1r1b
  • ppp1r1b.S
Epitope
AA 95-204
49
45
15
13
7
6
4
4
4
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
205
155
145
20
16
16
11
6
6
4
4
1
1
1
1
Host
Mouse
207
14
2
2
1
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
8
7
7
7
7
7
7
3
2
2
2
2
2
2
2
Application
ELISA, Western Blotting (WB)
148
73
66
30
27
27
8
8
6
6
5
2
1
Options
Immunogen Purified recombinant fragment of human PPP1R1B (AA 95-204) expressed in E. Coli.
Clone 2A4G9
Isotype IgG1
Purification Purified
Antigen
Alternative Name PPP1R1B (PPP1R1B Antibody Abstract)
Background This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. ,
Molecular Weight 23 kDa
Gene ID 84152
HGNC 84152
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) (AA 95-204) antibody (ABIN1724915) anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) (AA 95-204) antibody (Image 1)
Image no. 2 for anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) (AA 95-204) antibody (ABIN1724915) anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) (AA 95-204) antibody (Image 2)
Image no. 3 for anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) (AA 95-204) antibody (ABIN1724915) anti-Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 1B (PPP1R1B) (AA 95-204) antibody (Image 3)
Product cited in: Kunii, Ikemoto, Wada, Yang, Kusakabe, Suzuki, Niwa: "Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study." in: Medical molecular morphology, Vol. 44, Issue 4, pp. 190-9, 2011 (PubMed).

Hamel, Bouchard, Ferrario, Hassan, Aguilar-Mahecha, Buchanan, Quenneville, Miller, Basik: "Both t-Darpp and DARPP-32 can cause resistance to trastuzumab in breast cancer cells and are frequently expressed in primary breast cancers." in: Breast cancer research and treatment, Vol. 120, Issue 1, pp. 47-57, 2010 (PubMed).

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