Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PRKAG1 antibody (AA 230-331)

PRKAG1 Reactivity: Human ELISA, IHC Host: Mouse Monoclonal 4A1G9 unconjugated
Catalog No. ABIN1724935
  • Target See all PRKAG1 Antibodies
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    Binding Specificity
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 230-331
    Reactivity
    • 46
    • 24
    • 7
    Human
    Host
    • 43
    • 3
    Mouse
    Clonality
    • 42
    • 4
    Monoclonal
    Conjugate
    • 26
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRKAG1 antibody is un-conjugated
    Application
    • 33
    • 28
    • 15
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purpose
    PRKAG1 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human PRKAG1 (AA: 230-331) expressed in E. Coli.
    Clone
    4A1G9
    Isotype
    IgG1
    Top Product
    Discover our top product PRKAG1 Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Zaha, Young: "AMP-activated protein kinase regulation and biological actions in the heart." in: Circulation research, Vol. 111, Issue 6, pp. 800-14, (2012) (PubMed).

    Oliveira, Zhang, Solis, Isackson, Bellahcene, Yavari, Pinter, Davies, Ge, Ashrafian, Walker, Carling, Watkins, Casadei, Redwood: "AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes." in: Circulation research, Vol. 110, Issue 9, pp. 1192-201, (2012) (PubMed).

  • Target
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    Alternative Name
    PRKAG1 (PRKAG1 Products)
    Background

    Description: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

    Aliases: AMPKG

    Molecular Weight
    37.6kDa
    Gene ID
    5571
    HGNC
    5571
    UniProt
    P54619
    Pathways
    AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effect
You are here:
Support