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PRKAG1 Products

(Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))

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The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008].

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Featured PRKAG1 Categories

PRKAG1 Antibodies

High quality antibodies with extensive validation data.

PRKAG1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PRKAG1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ICC, FACS, IHC, ELISA, WB
Validations
  • (2)
  • (7)
Cat. No. ABIN1724932
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application ELISA, IF, IHC, WB
Validations
  • (3)
Cat. No. ABIN7142682
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application IF, WB
Validations
  • (3)
Cat. No. ABIN948313
Quantity 100 μg
Datasheet Datasheet

Recommended PRKAG1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3088262
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3131815
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316233
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our PRKAG1 products

Zaha, Young: "AMP-activated protein kinase regulation and biological actions in the heart." in: Circulation research, Vol. 111, Issue 6, pp. 800-14, (2012) (PubMed).

Oliveira, Zhang, Solis, Isackson, Bellahcene, Yavari, Pinter, Davies, Ge, Ashrafian, Walker, Carling, Watkins, Casadei, Redwood: "AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes." in: Circulation research, Vol. 110, Issue 9, pp. 1192-201, (2012) (PubMed).

Lin, Kiihl, Suhail, Liu, Chou, Kuang, Lu, Khor, Lin, Bader, Irizarry, Boeke: "Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK." in: Nature, Vol. 482, Issue 7384, pp. 251-5, (2012) (PubMed).

Greer, Oskoui, Banko, Maniar, Gygi, Gygi, Brunet: "The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor." in: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 30107-19, (2007) (PubMed).

Minokoshi, Alquier, Furukawa, Kim, Lee, Xue, Mu, Foufelle, Ferré, Birnbaum, Stuck, Kahn: "AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus." in: Nature, Vol. 428, Issue 6982, pp. 569-74, (2004) (PubMed).

Hamilton, Stapleton, ODonnell, Kung, Dalal, Kemp, Witters: "An activating mutation in the gamma1 subunit of the AMP-activated protein kinase." in: FEBS letters, Vol. 500, Issue 3, pp. 163-8, (2001) (PubMed).

Synonyms and alternative names related to PRKAG1

protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog (prkag1.S), protein kinase, AMP-activated, gamma 1 non-catalytic subunit (prkag1), protein kinase AMP-activated non-catalytic subunit gamma 1 (PRKAG1), protein kinase AMP-activated non-catalytic subunit gamma 1 (Prkag1), protein kinase, AMP-activated, gamma 1 non-catalytic subunit (Prkag1), AA571379, AMPKG, BB036179, MGC68503, Prkaac, Prkga1, wu:fa94d09, wu:fd12h04, zgc:63896

Protein level used designations for PRKAG1

  • protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • 5'-AMP-activated protein kinase subunit gamma-1
  • AMPK-activated protein kinase gamma-1 subunit
  • AMP-activated protein kinase, noncatalytic gamma-1 subunit
  • 5'-AMP-activated protein kinase subunit gamma-1-like
  • 5'-AMP-activated protein kinase, gamma-1 subunit
  • AMPK gamma-1 chain
  • AMPK gamma1
  • AMPK subunit gamma-1
  • AMPKg
  • Protein kinase AMP-activated gamma
  • 38 kDa subunit
  • 5'-AMP-activated protein kinase gamma-1 subunit
  • AMP-activated protein kinase subunit gamma 1 (non-catalytic subunit)
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