ADCYAP1R1 antibody (Extracellular Domain, N-Term)

Catalog No. ABIN1731542

Product Details anti-ADCYAP1R1 Antibody

Target: ADCYAP1R1 (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1))

Binding Specificity: Extracellular Domain, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADCYAP1R1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with human ADCYAP1R1

Cross-Reactivity (Details): BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Purification: Antigen affinity purified

Immunogen: Synthetic 17 amino acid peptide from N-terminal extracellular domain of human ADCYAP1R1. Percent identity with other species by BLAST analysis: Human (100%), Gibbon (100%), Monkey (100%), Marmoset (100%), Elephant (100%), Gorilla (94%), Panda (94%)

Isotype: IgG

Application Details

Application Notes:

Working dilution: IHC - P (7 μg/mL

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Long term: -70°C, Short term: +4°C

Target Details for ADCYAP1R1

Target: ADCYAP1R1 (Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I (ADCYAP1R1))

Alternative Name: ADCYAP1R1 (ADCYAP1R1 Products)

Background: This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.

UniProt: P41586

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process