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Axin antibody (Axin 1) C-Term Primary Antibody

AXIN1 Reactivity: Human, Mouse, Rat, Cow, Dog IHC (p), ELISA Host: Goat Polyclonal unconjugated
Catalog No. ABIN1732156
$800.80
Plus shipping costs $45.00
50 μg
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  • Target See all Axin (AXIN1) Antibodies
    Axin (AXIN1)
    Binding Specificity
    • 21
    • 15
    • 15
    • 15
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 7
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 94
    • 68
    • 36
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog
    Host
    • 125
    • 7
    • 7
    Goat
    Clonality
    • 132
    • 7
    Polyclonal
    Conjugate
    • 42
    • 12
    • 11
    • 11
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    This Axin antibody is un-conjugated
    Application
    • 94
    • 56
    • 39
    • 39
    • 38
    • 11
    • 9
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA
    Specificity
    Reacts with the C-terminus part of human AXIN1
    Cross-Reactivity
    Mouse (Murine), Cow (Bovine), Dog (Canine), Rat (Rattus)
    Cross-Reactivity (Details)
    Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.
    Purification
    Antigen affinity purified
    Immunogen
    Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1, NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)
  • Application Notes

    Working dilution: ELISA (1:128000), IHC-P (3.75 μg/mL)

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Minimize freezing and thawing.
  • Target
    Axin (AXIN1)
    Alternative Name
    AXIN1 (AXIN1 Products)
    Synonyms
    AXIN1, axin, fused, xAxin, LOC100226467, AXIN, PPP1R49, AI316800, Axin, Fu, Kb, Ki, kinky, knobbly, AXIN1-RGS, wu:fi22e03, wu:fj14c08, wu:fk11b03, zgc:109872, axin 1, axin 1 S homeolog, axin 1 L homeolog, AXIN1, axin1.S, axin1.L, Axin1, axin1
    Background
    Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
    UniProt
    O15169
    Pathways
    WNT Signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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