Neuroligin 1 antibody (Extracellular Domain)

Catalog No. ABIN1742286

Product Details anti-Neuroligin 1 Antibody

Target: Neuroligin 1 (NLGN1)

Binding Specificity: AA 46-165, Extracellular Domain

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuroligin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Specific for neuroligin 1

Cross-Reactivity (Details): no cross reactivity to neuroligins 2, 3, 4.

Purification: Affinity purified with the immunogen. Rabbit serum albumin was added for stabilization.

Immunogen: Recombinant protein of rat neuroligin 1 containing the extracellular sequence (aa 46-165).

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
IP: not tested yet
ICC: not recommended
IHC: not recommended

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 µL H2O to get a 1mg/ml solution of antibody in PBS. Then aliquot and store at -20 °C until use.

Buffer: PBS

Handling Advice: Affinity purified antibodies are less robust than antisera, since protease inhibitors are also removed during purification. Hence, storage at 4 °C for prolonged periods (i.e. several weeks), is not recommended.

Storage: -20 °C

Storage Comment: Unlabeled lyophilized antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4°C for several years. Lyophilized antibodies must not be stored in the freezer, they may be destroyed!

References for anti-Neuroligin 1 antibody (ABIN1742286)

Dahlhaus, Hines, Eadie, Kannangara, Hines, Brown, Christie, El-Husseini: "Overexpression of the cell adhesion protein neuroligin-1 induces learning deficits and impairs synaptic plasticity by altering the ratio of excitation to inhibition in the hippocampus." in: Hippocampus, Vol. 20, Issue 2, pp. 305-22, (2010) (PubMed).

Target Details for Neuroligin 1

Target: Neuroligin 1 (NLGN1)

Alternative Name: Neuroligin 1 (NLGN1 Products)

Synonyms: NLGN1 antibody, Nlgn1 antibody, GB18720 antibody, nlgn1 antibody, NL1 antibody, 6330415N05Rik antibody, BB179718 antibody, mKIAA1070 antibody, neuroligin-1 antibody, neuroligin 1 antibody, NLGN1 antibody, LOC659779 antibody, LOC724358 antibody, nlgn1 antibody, Nlgn1 antibody

Pathways: Synaptic Membrane, Synaptic Vesicle Exocytosis