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Neuroligin 1 antibody (AA 718-843)

NLGN1 Reactivity: Rat WB, IHC, ICC, IF Host: Mouse Monoclonal S97A-31 unconjugated
Catalog No. ABIN1741305
  • Target See all Neuroligin 1 (NLGN1) Antibodies
    Neuroligin 1 (NLGN1)
    Binding Specificity
    • 20
    • 16
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 718-843
    Reactivity
    • 41
    • 37
    • 26
    • 1
    Rat
    Host
    • 34
    • 26
    • 1
    Mouse
    Clonality
    • 38
    • 23
    Monoclonal
    Conjugate
    • 23
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neuroligin 1 antibody is un-conjugated
    Application
    • 53
    • 27
    • 25
    • 14
    • 13
    • 12
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Specificity
    Detects ~120 kDa. Does not cross-react with other Neuroligins.
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Protein G Purified
    Immunogen
    Fusion protein amino acids 718-843 (cytoplasmic C-terminus) of rat Neuroligin-1. Mouse: 99% identity (125/126 amino acids identical). Human: 99% identity (125/126 amino acids identical) >40% identity with Neuroligin-2 and -3.
    Clone
    S97A-31
    Isotype
    IgG1
    Top Product
    Discover our top product NLGN1 Primary Antibody
  • Application Notes
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Comment

    2 μg/ml of ABIN1741305 was sufficient for detection of Neuroligin-1 in 20 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C
  • Target
    Neuroligin 1 (NLGN1)
    Alternative Name
    Neuroligin 1 (NLGN1 Products)
    Synonyms
    NLGN1 antibody, Nlgn1 antibody, GB18720 antibody, nlgn1 antibody, NL1 antibody, 6330415N05Rik antibody, BB179718 antibody, mKIAA1070 antibody, neuroligin-1 antibody, neuroligin 1 antibody, NLGN1 antibody, LOC659779 antibody, LOC724358 antibody, nlgn1 antibody, Nlgn1 antibody
    Background
    Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.
    Gene ID
    116647
    UniProt
    Q62765
    Pathways
    Synaptic Membrane, Synaptic Vesicle Exocytosis
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