SRA1 antibody (AA 519-556)

Catalog No. ABIN1742561

There are 2+ publications for this product available. The Mouse Monoclonal anti-SRA1 antibody is suitable to detect SRA1 in samples from Human, Rat and Mouse. It has been validated for WB and IP.

Quick Overview for SRA1 antibody (AA 519-556) (ABIN1742561)

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This SRA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 30A4

Product Details anti-SRA1 Antibody

Binding Specificity: AA 519-556

Purpose: Mouse anti-Sra1 IgG

Specificity: Specific for Sra 1

Cross-Reactivity (Details): Reacts with: human (Q7L576), rat, mouse (Q7TMB8). Other species not tested yet.

Purification: purified IgG

Immunogen: Synthetic peptide corresponding to AA 519 to 556 from mouse Sra1 (UniProt Id: Q7TMB8)

Isotype: IgG1

Application Details

Application Notes: WB:1 : 100 up to 1 : 2000 , IP:yes ICC:not recommended IHC:not recommended IHC-P:not tested yet

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Azide was added before lyophilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

References for anti-SRA1 antibody (ABIN1742561)

Bozdagi, Sakurai, Dorr, Pilorge, Takahashi, Buxbaum: "Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice." in: PLoS ONE, Vol. 7, Issue 8, pp. e42422, (2012) (PubMed).

Steffen, Faix, Resch, Linkner, Wehland, Small, Rottner, Stradal: "Filopodia formation in the absence of functional WAVE- and Arp2/3-complexes." in: Molecular biology of the cell, Vol. 17, Issue 6, pp. 2581-91, (2006) (PubMed).

Target Details for SRA1

Target: SRA1 (Steroid Receptor RNA Activator 1 (SRA1))

Alternative Name: Sra1

Background:

Synonyms: CYFIP 1, FMR1-interacting protein 1

Antigen Information: Sra1 is involved in the initiation of actin polymerization

UniProt: Q7TMB8

Pathways: EGFR Signaling Pathway, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development