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Natural Cytotoxicity Triggering Receptor 2 (NCR2) antibody Primary Antibody

NCR2 Reactivity: Human, Mouse, Rat IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2432791
$493.90
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  • Target
    Natural Cytotoxicity Triggering Receptor 2 (NCR2)
    Reactivity
    Human, Mouse, Rat
    Host
    Rabbit
    Clonality
    Polyclonal
    Conjugate
    Un-conjugated
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Application
    Immunohistochemistry (IHC), ELISA
    • 13
    • 13
    • 8
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    Purification
    Antigen affinity purification
    Immunogen
    Synthetic peptide of human NCR2
    Isotype
    IgG
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Handling Advice
    Avoid freeze / thaw cycles.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C (regular) and -80°C (long term).
  • Target
    Natural Cytotoxicity Triggering Receptor 2 (NCR2)
    Alternative Name
    NCR2 (NCR2 Antibody Abstract)
    Synonyms
    CD336, LY95, NK-p44, NKP44, dJ149M18.1, uncharacterized LOC609023, natural cytotoxicity triggering receptor 2, LOC609023, NCR2
    Background
    Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene. NCR2 has also been designated as CD336 (cluster of differentiation 336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load.
    Synonyms: LY95, CD336, NKP44, NK-p44, dJ149M18.1
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